Pharm Sci Seminar – Tadhg Begley, PhD
This lecture will describe recent mechanistic studies on futalosine-dependent menaquinone biosynthesis and the development of new radical trapping strategies.
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This lecture will describe recent mechanistic studies on futalosine-dependent menaquinone biosynthesis and the development of new radical trapping strategies.
The development of a quality pharmaceutical tablet product is a complex process, involving informed decisions on the type and amount of excipients and several process parameters. Owning to the level of complexity, tablet development has been empirical.
Dr. Howard Jacob, a leader in the genetics and genomics fields, will speak about the growing role of genome sequencing in medication management and the pivotal role that pharmacists play in pharmacogenomics and precision medicine in his talk "Better Care, Better Management of Medications and Better Health through Genome Sequencing".
Presentation Title: Solid-State Pharmaceutical Sciences: Past, Present and Future. Understanding both the solid-state chemistry and material properties of a drug molecule is essential to the development of a medicine. However, solid-state pharmaceutical science as a discipline was largely unrecognized in some sectors even two or three decades ago.
The effective treatment of antibiotic-resistant bacterial infections is an unmet clinical need that is of increasing urgency. The deployment of nanoparticles, specifically targeted to the diseased tissues and carrying payloads designed to either enhance existing therapeutic regimens or to reprogram the immune system response will be described.
Small molecule drugs mostly have molecular weight of less than 500, but they exert large structural diversity as they bind to various drug targets. Drug metabolism by Phase-I and Phase-II enzymes further increases such structural diversity.
Employing a structure/function approach to the understanding of the molecular topology of growth hormone (GH), we discovered that glycine (Gly) 119 of bovine GH and Gly 120 of human GH were important amino acids required for GH activity.
Professor Dale Wurster from the University of Iowa College of Pharmacy will give the 2019 Busse Lecture on "Determination of Adsorption Site Specificity – Activated Carbon as a Model".
Professor Dale Wurster from the University of Iowa College of Pharmacy will give the second 2019 Busse Lecture on "Compression Calorimetry".
Join us on April 5 at 3:30pm for Dr. Janet Smith's Hutchinson lecture, "Natural Product Biosynthetic Enzymes: Not All Domains Are What They Appear to Be".