School of Pharmacy UNIVERSITY OF WISCONSIN - MADISON Drug Discovery Core Research in Drug Discovery at the University of Wisconsin focuses on areas related to medicinal chemistry, such as small molecule development, natural products isolation and characterization, organic synthesis, and rational drug design. The School of Pharmacy’s Analytical Instrumentation Center offers state of the art instrumentation to expedite the isolation and full structural elucidation of the many diverse small molecules generated via the Discovery Core. In collaboration with the Pharmaceutical Sciences Drug Action and Drug Delivery Cores, these chemical entities can be subsequently evaluated via high throughput screening toward lead generation or specifically utilized to probe novel biological phenomenon toward in-depth mechanistic study. Thus, the UW Pharmaceutical Sciences Drug Discovery Core presents the student with intensive training in modern organic chemistry coupled with a distinctive exposure to the modern applications of small molecules within biology and medicine. State of the art analytical capabilities (School of Pharmacy AIC) Centralized Facilities for Computer-Aided Drug and Catalyst Design Cutting Edge Instrumentation for High Throughput Synthesis, Analysis and Purification of Small Molecule Libraries Drug Discovery Services (Medicinal Chemistry Center) Robotic Liquid Handling Systems for High Throughput Analysis of Chemical Libraries and New Catalysts Students within the UW Pharmaceutical Sciences Drug Discovery Core are eligible for a number of diverse traineeships including the Chemistry-Biology Interface and the Biotechnology Training Programs DISCOVERY CORE FACULTY: Bugni, Golden, Hsung, Jiang, Kwan, Lauhon, Li, Mecozzi, Swanson, Tang, Weichert.