Drug Delivery Core

The Drug Delivery Core continues a longstanding tradition in education, research, and outreach in pharmaceutical sciences in the School of Pharmacy at the University of Wisconsin-Madison. Faculty members, graduate students, and postdoctoral researchers have made many seminal discoveries in drug delivery, noting the historical significance of research in physical pharmacy, first initiated at the school. The Drug Delivery Core strives to offer exemplary graduate studies that emphasize fundamental principles in physical chemistry, and drug transport, aiming for advances in formulation, drug targeting, and multi-modal therapy:

  • We carry out internationally-recognized research in solid state chemistry of drugs, nanomedicine, biocompatibility, molecular recognition, computational chemistry, drug transport in the brain, and molecular imaging, funded by National Institutes of Health (NIH), National Science Foundation (NSF), and the pharmaceutical industry.
  • We offer an interdisciplinary curriculum that reveals the multi-faceted nature of the process of drug development buttressed by strengths in drug discovery and drug action, recognizing that major breakthroughs in the pharmaceutical sciences will require interdisciplinary teams.
  • We foster relationships with the pharmaceutical industry and other universities to strengthen research and education in our graduate program through collaborative projects, mentorship, internships, study abroad programs, offering unique opportunities for career advancement.
  • We support outreach in the Division of Pharmacy Professional Development and active participation in national and international organizations including the American Association of Pharmaceutical Scientists (UW AAPS Student Chapter), the American Association of Colleges of Pharmacy, the Controlled Release Society, the Society of Biomaterials, and the American Chemical Society.  We interact and consult for the school’s Zeeh Pharmaceutical Experiment Station.

We invite you to contact us and join the Drug Delivery Core for graduate or postdoctoral studies featuring stellar drug delivery research programs, and leading to rewarding careers in the pharmaceutical and biotechnology industries, academia, or government.

 


DRUG DELIVERY CORE FACULTY : Albrecht, Burnette, de Villiers, Hong, KwonMecozzi, Taylor, Thorne, Weichert, Yu.

Research Areas in the Drug Delivery Core

Molecular Recognition

  • Computational chemistry
  • Fluorous materials
  • Host-guest interactions
  • NMR
  • Self-assembly
  • Structural chemistry

Nanopharmacy

  • Biomimetic nanotechnology
  • Layer-by-layer assembly
  • Non-viral gene delivery
  • Polymeric micelles & nanomaterials
  • Dendritic polymers
  • Nanoemulsions
  • Nanometer/micrometer sized drug delivery systems
  • Nanotoxicology
  • PEGylation

Pharmacokinetics / Pharmacodynamics

  • Blood-brain-barrier
  • Brain drug transport
  • Central nervous system delivery
  • Distribution of biologics (peptides, proteins, siRNA nanoparticles, viral gene vectors)
  • Regulation of multidrug resistance transporters
  • siRNA targeting
  • Targeted drug delivery
  • Tumor targeting

Solid-state Chemistry

  • Amorphous pharmaceuticals
  • Crystallization
  • Molecular glasses
  • Pharmaceutical materials science
  • Polymorphism
  • Solid-state stability
  • Surface mobility
  • Particle engineering
  • Controlled release

Additional Opportunities

  • Molecular imaging
  • Neurological diseases
  • Cancer diagnostics/prognostics
  • Cancer immunotherapy
  • Imaging of cardiovascular disease and diabetes
  • Image-guided drug delivery
  • Infectious diseases
  • Liquid biopsy technology
  • Therapy agents for oncology applications