Pharmaceutical Sciences Seminar Series
- Juliane Nguyen, PhD
- Eshelman School of Pharmacy, University of North Carolina at Chapel Hill
Developing Therapeutic Materials to Redirect Cellular Chatter
An increasing number of studies report that exosomes play critical roles in intercellular communication. While exosomes are essential for maintaining physiological conditions, aberrant exosomal communication can lead to the development of cancer, diabetes, and many other diseases.
Here we will describe new materials to redirect and modulate cellular communication mediated by exosomes for therapeutic applications. Specifically, we have identified RNA-based materials to modulate exosomal function by repackaging them with various cargoes. This presentation will also discuss strategies to enhance beneficial exosomal communication for therapeutic purposes.
Hosted by Professor Seungpyo Hong