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University of Wisconsin-Madison

Infectious disease research by Rose and colleagues is among most significant in 2014

A recent publication resulting from a collaboration with Warren Rose, associate professor (CHS), and colleagues from the departments of pharmacy and medicine at the University of Wisconsin Hospital and Clinics was highlighted as the 6th ranked most significant publication on infectious diseases pharmacotherapy in 2014 by the Society of Infectious Diseases Pharmacists (SIDP).

The study published in Antimicrobial Agents and Chemotherapy was a clinical evaluation of outcomes of daptomycin dosing using a novel ideal body weight dose compared to conventional total body weight dosing. The retrospective study found no difference in outcomes between the two dosing regimens. The publication provides important clinical significance to infectious diseases practitioners and antimicrobial stewardship pharmacists to potentially reduce drug toxicity and treatment costs with daptomycin while still achieving quality outcomes. The investigators are continuing to evaluate this regimen in special populations at UW Health.

The paper was nominated among a list of 19 significant articles selected from over 19,000 publications in the field of infectious diseases in 2014, and the final ranking was compiled by a national online survey of SIDP members. “Significant publications on infectious diseases pharmacotherapy in 2014” is published in the August 15, 2015 issue of the American Journal of Health-Systems Pharmacy (AJHP).

The AJHP is the official publication of the American Society of Health-System Pharmacists (ASHP). It publishes peer reviewed scientific papers on contemporary drug therapy and pharmacy practice innovations in hospitals and health systems. With a circulation of nearly 40,000, AJHP is the most widely recognized and respected clinical pharmacy journal in the world. Articles in AJHP are abstracted and indexed in PubMed and many other scientific databases.