Publications

Wenthur CJ, Gautam R, Zhou B, Vendruscolo LF, Leggio L, Janda KD. Ghrelin Receptor Influence on Cocaine Reward is Not Directly Dependent on Peripheral Acyl-Ghrelin. Scientific Reports, 9(1):1841. 2019.

Hwang CS, Bremer PT, Wenthur CJ, Ho SO, Chiang S, Ellis B, Zhou B, Fujii G, Janda KD. Enhancing efficacy and stability of an anti-heroin vaccine: Examination of antinociception, opioid binding profile, and lethality. Molecular Pharmaceutics, 15; (3):1062-1072. 2018.

Wenthur CJ, Zhao B, Janda KD. Vaccine-driven pharmacologic dissection and mitigation of fenethylline psychoactivity. Nature, 548; (7668):476-479. 2017.

Wenthur CJ, Cai X, Ellis BA, Janda KD. Augmenting the efficacy of anti-cocaine catalytic antibodies through chimeric hapten design and combinatorial vaccination. Bioorganic and Medicinal Chemistry Letters. 27; (16):3666-3668. 2017.

Gooyit MD*, Miranda PO*, Wenthur CJ*, Ducime A, Janda KD. Influencing antibody-mediated attenuation of methamphetamine CNS distribution through vaccine linker design. ACS Chemical Neuroscience. 8; (3):468-472. 2017.

Kimishima A, Wenthur CJ, Zhou B, Janda KD. An advance in prescription opioid vaccines: Overdose mortality reduction and extraordinary alteration of drug half-life. ACS Chemical Biology. 12; (1):36-40. 2017.

Wenthur CJ. Classics in chemical neuroscience: Methylphenidate. ACS Chemical Neuroscience. 7; (8):1030-40. 2016.

Kimishima A*, Wenthur CJ*, Eubanks LM, Sato S, Janda KD. Cocaine vaccine development: Evaluation of carrier and adjuvant combinations that activate multiple toll-like receptors. Molecular Pharmaceutics. 13; (11):3884-3890. 2016.

Harris TL*, Wenthur CJ*, Diego-Taboada A, Mackenzie G, Corbitt TS, Janda KD. Lycopodium clavatum exine microcapsules enable safe oral delivery of 3,4-diaminopyridine for treatment of botulinum neurotoxin A intoxication. Chemical Communications. 52: 4187-90. 2016.

Walker AG*, Wenthur CJ*, Xiang Z, Rook JM, Emmitte KA, Lindsley CW, Conn PJ. Metabotropic glutamate receptor 3 (mGlu3) activation is required for group II mGlu long-term depression in the medial prefrontal cortex and fear extinction learning. Proceedings of the National Academy of Sciences USA. 112; (4):1196-201. 2015.

Wenthur CJ, Gentry PR, Mathews TP, Lindsley CW. Drugs for allosteric sites on receptors. Annual Reviews in Pharmacology and Toxicology. 54: 165-84. 2014.

Wenthur CJ, Morrison RD, Daniels JS, Conn PJ, Lindsley CW. Synthesis and SAR of substituted pyrazolo[1,5-a]quinazolines as dual mGlu(2)/mGlu(3) NAMs. Bioorganic and Medicinal Chemistry Letters. 24; (12):2693-8. 2014.

Wenthur CJ, Bennett MR, Lindsley CW. Classics in chemical neuroscience: Fluoxetine (ProzacTM). ACS Chemical Neuroscience. 5; (1): 14-23. 2014.

Wenthur CJ, Morrison R, Felts AS, Smith KA, Engers JL, Byers FW, Daniels JS, Emmitte KA, Conn PJ, Lindsley CW. Discovery of (R)-(2-fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-hydroxypiperidin-1-yl)methanone (ML337), an mGlu3 selective and CNS penetrant negative allosteric modulator (NAM). Journal of Medicinal Chemistry 56; (12):5208-12. 2013.

Schellhase E, Liu E, Pastakia S, Wenthur CJ, Murawski MM, Jakait B, Wasike P. The development of care focused adherence-tracking dispensing database for HIV care in a resource-constrained setting. Journal of Pharmaceutical Health Services Research 4; (1):63-67. 2013.

Wenthur CJ, Romack BS, Vernon VP, Shelly JL, Harth BN, Lienhoop AD, Madison NR, Murawski MM. Opinions and experiences of Indiana pharmacists and student pharmacists: The need for substance abuse education. Research in Social and Administrative Pharmacy 9; (1):90-100. 2013.

Wenthur CJ, Lindsley CW. Classics in chemical neuroscience: Clozapine. ACS Chemical Neuroscience 4; (7):1018-25. 2013.

Sheffler DJ*, Wenthur CJ*, Bruner JA*, Carrington SJ, Vinson PN, Gogi KK, Blobaum AL, Morrison RD, Vamos M, Cosford ND, Stauffer SR, Daniels JS, Niswender CM, Conn PJ, Lindsley CW. Development of a novel, CNS-penetrant, metabotropic glutamate receptor 3 NAM probe derived from a closely related mGlu5 PAM. Bioorganic and Medicinal Chemistry Letters 22; (12):3921-5. 2012.                             

Wenthur CJ, Rodriguez GJ, Kuntz CP, Barker EL. Conformational flexibility of transmembrane helix VII of the human serotonin transporter impacts ion dependence and transport. Biochemical Pharmacology 80; (9):1418-426. 2010.