Publications

Kimishima, A., Wenthur, C. J., Zhou, B., & Janda, K. D. (2017). An Advance in Prescription Opioid Vaccines: Overdose Mortality Reduction and Extraordinary Alteration of Drug Half-Life. ACS chemical biology, 12(1), 36–40. https://doi.org/10.1021/acschembio.6b00977

Kimishima, A., Wenthur, C. J., Eubanks, L. M., Sato, S., & Janda, K. D. (2016). Cocaine Vaccine Development: Evaluation of Carrier and Adjuvant Combinations That Activate Multiple Toll-Like Receptors. Molecular pharmaceutics, 13(11), 3884–3890. https://doi.org/10.1021/acs.molpharmaceut.6b00682

Wenthur C. J. (2016). Classics in Chemical Neuroscience: Methylphenidate. ACS chemical neuroscience, 7(8), 1030–1040. https://doi.org/10.1021/acschemneuro.6b00199

Walker, A. G., Wenthur, C. J., Xiang, Z., Rook, J. M., Emmitte, K. A., Niswender, C. M., Lindsley, C. W., & Conn, P. J. (2015). Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction. Proceedings of the National Academy of Sciences of the United States of America, 112(4), 1196–1201. https://doi.org/10.1073/pnas.1416196112

Wenthur, C. J., Morrison, R. D., Daniels, J. S., Conn, P. J., & Lindsley, C. W. (2014). Synthesis and SAR of substituted pyrazolo[1,5-a]quinazolines as dual mGlu(2)/mGlu(3) NAMs. Bioorganic & medicinal chemistry letters, 24(12), 2693–2698. https://doi.org/10.1016/j.bmcl.2014.04.051

Wenthur, C. J., Gentry, P. R., Mathews, T. P., & Lindsley, C. W. (2014). Drugs for allosteric sites on receptors. Annual review of pharmacology and toxicology, 54, 165–184. https://doi.org/10.1146/annurev-pharmtox-010611-134525

Wenthur, C. J., & Lindsley, C. W. (2013). Classics in chemical neuroscience: clozapine. ACS chemical neuroscience, 4(7), 1018–1025. https://doi.org/10.1021/cn400121z

Wenthur, C. J., Morrison, R., Felts, A. S., Smith, K. A., Engers, J. L., Byers, F. W., Daniels, J. S., Emmitte, K. A., Conn, P. J., & Lindsley, C. W. (2013). Discovery of (R)-(2-fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-hydroxypiperidin-1-yl)methanone (ML337), an mGlu3 selective and CNS penetrant negative allosteric modulator (NAM). Journal of medicinal chemistry, 56(12), 5208–5212. https://doi.org/10.1021/jm400439t

Wenthur, C. J., Cross, B. S., Vernon, V. P., Shelly, J. L., Harth, B. N., Lienhoop, A. D., Madison, N. R., & Murawski, M. M. (2013). Opinions and experiences of Indiana pharmacists and student pharmacists: the need for addiction and substance abuse education in the United States. Research in social & administrative pharmacy : RSAP, 9(1), 90–100. https://doi.org/10.1016/j.sapharm.2012.03.003

Sheffler, D. J., Wenthur, C. J., Bruner, J. A., Carrington, S. J., Vinson, P. N., Gogi, K. K., Blobaum, A. L., Morrison, R. D., Vamos, M., Cosford, N. D., Stauffer, S. R., Daniels, J. S., Niswender, C. M., Conn, P. J., & Lindsley, C. W. (2012). Development of a novel, CNS-penetrant, metabotropic glutamate receptor 3 (mGlu3) NAM probe (ML289) derived from a closely related mGlu5 PAM. Bioorganic & medicinal chemistry letters, 22(12), 3921–3925. https://doi.org/10.1016/j.bmcl.2012.04.112