Publications: 2013-2017

  1. “AB3-loaded and tumor-targeted unimolecular micelles for medullary thyroid cancer treatment.”
    Jaskula-Sztul, R.; Chen, G.; Dammalapati, A.; Harrison, A.; Tang, W.; Gong, S.;* and Chen, H.* J. Mater. Chem. 20175151-159link.
  2. “Addressing the Challenge of Carbohydrate Site Selectivity by Synergistic Catalysis.”
    Blaszczyk, S. A. and Tang W.* Chem 20173, 722–723. link.
    Thumbnail for publication 75
  3. “Isoquinoline-1-carboxylate as a Traceless Leaving Group for Chelation-Assisted Glycosylation under Mild Neutral Conditions.”
    Wang, H.-Y.; Simmons, C. J.; Blaszczyk, S. A.; Balzer, P. G.; Luo, R.; Duan, X.; and Tang W.* Angew. Chem. Int. Ed. 201756, 15698–15702 . linkSoP News.thumbnail for publication 74
  4. “Harnessing the Reactivity of Iridium Hydrides by Air: Iridium- Catalyzed Oxidation of Aldehydes to Acids in Water.”
    Yang, Z.; Luo, R.; Zhu, Z.; Yang, X.; and Tang W.* Organometallics201736, 4095–4098. link.
  5. “Transition metal mediated carbonylative benzannulations.”
    Song, W.; Blaszczyk, S. A.; Liu, J.; Wang, S.;* and Tang W.* Org. Biomol. Chem. 201715, 7490-7504. link. thumbnail for publication 72
  6. “Iridium-catalyzed highly efficient chemoselective reduction of aldehydes in water using formic acid as the hydrogen source.”
    Yang, Z.; Zhu, Z.; Luo, R.; Qiu, X.; Liu, J.-L.; Yang, J.-K.; and Tang W.* Green Chem. 201719, 3296-3301. link.
    Thumbnail for publication 71
  7. De novo Synthesis of Mono- and Oligosaccharides via Dihydropyran Intermediates.”
    Song, W.; Wang, S.* and Tang, W.* Chem. Asian J. 201712, 1027-1042. link.
    thumbnail for publication 70
  8. “Catalytic Site-Selective Acylation of Carbohydrates Directed by Cation–n Interaction.”
    Xiao, G.; Cintron-Rosado, G. A.; Glazier, D. A.; Xi, B.-m.; Liu, C.; Liu, P.* and Tang, W.* J. Am. Chem. Soc. 2017139, 4346-4349. link. SoP News.
  9. “Neuroendocrine Tumor-Targeted Upconversion Nanoparticle-Based Micelles for Simultaneous NIR-Controlled Combination Chemotherapy and Photodynamic Therapy, and Fluorescence Imaging.”
    Chen, G.; Jaskula-Sztul, R.; Esquibel, C. R.; Lou, I.; Zheng, Q.; Dammalapati, A.; Harrison, A.; Eliceiri, K. W.; Tang, W.; Chen, H.;* Gong, S.* Adv. Funct. Mater. 201727, 1604671. link.
  10. “Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Anomeric Hydroxyl Groups and a Controlled Reduction of the Glycosyl Ester Products.”
    Wang, H.-Y.; Simmons, C. J.; Zhang, Y.; Smits, A. M.; Balzer, P. G.; Wang, S.;* and Tang, W.* Org. Lett. 201719, 508-511link.
  11. “Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation.”
    Liu, J.-t.; Simmons, C. J.; Xie, H.; Yang, F.; Zhao, X-l.;* Tang, Y.;* and Tang, W.* Adv. Syn. Catal. 2017359, 693-697link. Highlight in Synfacts, 2017, 13(05): 0478 (DOI: 10.1055/s-0036-1590363).thumbnail for publication 66
  12. “Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma.”
    Hideshima, T.; Qi, J.; Paranal, R. M.; Tang, W.; Greenberg, E.; West, N.; Colling, M. E.; Estiu, G.; Mazitschek, R.; Perry, J. A.; Ohguchi, H.; Cottini, F.; Mimura, N.; Görgün, G.; Tai, Y.-T.; Richardson, P. G.; Carrasco, R. D.; Wiest, O.; Schreiber, S. L.; Anderson, K. C.;* Bradner, J. E.* Proc. Natl. Acad. Sci. U.S.A. 2016113, 13162-13167link.
  13. “Author Profile ” Tang, W. Angew. Chem. Int. Ed. 201655, 12142. link.
  14. “Total Synthesis of Diptoindonesin G and Its Analogues as Selective Modulators of Estrogen Receptors.”
    Liu, J.-t.; Do, T. J.; Simmons, C. J.; Lynch, J. C.; Gu, W.; Ma, Z.-X.; Xu, W.; and Tang, W.* Org. Biomol. Chem. 201614, 8927-8930link.Thumbnail for publication 63: Graphical abstract: Total synthesis of diptoindonesin G and its analogues as selective modulators of estrogen receptors
  15. “Rhodium(I)-Catalyzed Benzannulation of Heteroaryl Propargylic Esters: Synthesis of Indoles and Related Heterocycles.”
    Li, X.; Xie, H.; Fu, X.; Liu, J.-t.; Wang, H.-y.; Xi, B.-m.;* Liu, P.;* Xu, X.;* and Tang, W.* Chem. Eur. J. 201622, 10410-10414. link.thumbnail for publication 62
  16. “Rhodium-catalyzed [5+2] Cycloaddition of 3-Acyloxy-1,4-enyne and Alkene or Allene.”
    Song, W.; Lynch, J. C.; Shu, X.-z.; and Tang, W.* Adv. Syn. Catal. 2016358, 2007-2011. link.thumbnail for publication 61
  17. “Rhodium-Catalyzed [5+2] Cycloaddition of Inverted 3-Acyloxy-1,4-enyne and Alkyne: Experimental and Theoretical Studies.”
    Li, X.; Song, W.; Zhao, X.-l.; Ke, X.; Xu, X.;* Liu, P.; Houk, K. N. and Tang, W.* Chem. Eur. J. 2016, 22, 7079-7083. link.
    thumbnail for publication 60
  18. “Synthesis of Carbazoles and Carbazole-Containing Heterocycles via Rhodium-Catalyzed Tandem Carbonylative Benzannulations.”
    Song, W.; Li, X.; Yang, K.; Zhao, X.-l.; Glazier, D. A.; Xi, B.-m.;* Tang, W.* J. Org. Chem. 2016, 81, 2930–2942. link.
    thumbnail for publication 58
  19. “Mechanism and reactivity of rhodium-catalyzed intermolecular [5+1] cycloaddition of 3-acyloxy-1,4-enyne (ACE) and CO: A computational study.”
    Ke, X.-N.; Schienebeck, C. M.; Zhou, C.-C.; Xu, X.-F.;* Tang, W.* Chin. Chem. Lett. 2015, 26, 730-734. link.
  20. “Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Lactols for De Novo Synthesis of Carbohydrate.”
    Wang, H.-Y.; Yang, K.; Yin, D.; Liu, C.; Glazier, D. A.; Tang, W.* Org. Lett. 2015, 17, 5272-5275. link.
    thumbnail for publication 56
  21. “Divergent De Novo Synthesis of All Eight Stereoisomers of 2,3,6-Trideoxyhexopyranosides and Their Oligomers.”
    Song, W.; Zhao, Y.;* Lynch, J. C.; Kim, H.; Tang, W.* Chem Commun. 2015, 51, 17475-17478. link.
  22. “Rhodium-Catalyzed Stereoselective Intramolecular [5 + 2] Cycloaddition of 3-Acyloxy 1,4-Enyne and Alkene.”
    Shu, X.-Z.; Schienebeck, C. M.; Li, X.; Zhou, X.; Song, W.; Chen, L.; Guzei, I. A.; Tang, W.* Org. Lett. 2015, 17, 5128-5131. link.
  23. “Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations.”
    Li, X.; Li, H.; Song, W.; Tseng, P.-S.; Liu, L.-Y.*; Guzei, I. A.; Tang, W.* Angew. Chem. Int. Ed. 2015, 54, 12905-12908. link.
    thumbnail for publication 53
  24. “Iridium-Catalyzed Dynamic Kinetic Isomerization: Expedient Synthesis of Carbohydrates from Achmatowicz Rearrangement Products.”
    Wang, H.-Y.; Yang, K.; Bennett S. R.; Guo, S.-R.;* Tang, W.* Angew. Chem. Int. Ed. 2015, 54, 8756–8759. link.
    thumbnail for publication 51
  25. “Novel Analogs Targeting Histone Deacetylase Suppress Aggressive Thyroid Cancer Cell Growth and Induce Re-differentiation.”
    Jang, S.; Yu, X. M.; Odorico, S.; Clark, M.; Jaskula-Sztul, R.; Schienebeck, C. M.; Kupcho, K. R.; Harrison, A. D.; Winston-McPherson, G. N.; Tang, W.; Chen, H.* Cancer Gene Ther. 2015, 22, 410. link.
  26. “Synthesis of Substituted Tropones by Sequential Rh-Catalyzed [5+2] Cycloaddition and Elimination.”
    Song, W.; Xi, B.-m.;* Yang, K.; Tang, W.* Tetrahedron 2015, 71, 5979-5984. (Invited contribution for Prof. Barry Trost’s Tetrahedron Award.). link.
    thumbnail for publication 49
  27. “Rhodium-Catalyzed Intermolecular [5+1] and [5+2] Cycloadditions Using 1,4-Enynes with an Electron-Donating Ester on the 3-Position.”
    Schienebeck, C. M.; Song, W.; Smits, A. M.; Tang, W.* Synthesis 2015, 47, 1076-1084. (invited feature article). link.
  28. “Tumor Suppressor Role of Notch3 in Medullary Thyroid Carcinoma Revealed by Genetic and Pharmacological Induction.”
    Jaskula-Sztul, R.; Eide, J.; Tesfazghi, S.; Dammalapati, A.; Harrison, A. D.; Yu, X.-M.; Scheinebeck, C.; Winston-McPherson, G.; Kupcho, K. R.; Robers, M. B.; Hundal, A. K.; Tang, W.;* Chen, H.* Mol. Cancer Therap. 2015, 14, 499. link.
  29. “Gold versus Rhodium: Divergent Reactivity Enabled by the Catalyst.”
    Winston-McPherson, G. N.; Tang, W.* ChemCatChem 2015, 7, 574-576. link.
    thumbnail for publication 46
  30. “Copper-catalyzed tandem annulation/arylation for the synthesis of diindolylmethanes from propargylic alcohols.”
    Li, H.; Li, X.; Wang, H.-Y.; Winston-McPherson, G. N.; Geng, H.-M. J.; Guzei, I. A.; Tang, W.* Chem. Commun. 2014, 50, 12293-12296. link.
    Thumbnail for publication 43: Graphical abstract: Copper-catalyzed tandem annulation/arylation for the synthesis of diindolylmethanes from propargylic alcohols
  31. “Synthesis of naturally occurring tropones and tropolones.”
    Liu, N.; Song, W.; Schienebeck, C. M.; Zhang, M.* Tang, W.* Tetrahedron. 2014, 70, 9281-9305. (Invited review) link.
    thumbnail image of tropone and tropolones (pub 42)
  32. “Synthesis and Biological Evaluation of 2,3’-Diindolylmethanes as Agonists of Aryl Hydrocarbon Receptor.”
    Winston-McPherson, G. N.; Shu, D.; Tang, W.* Bioorg. Med. Chem. Lett. 2014, 24, 4023-4025. link.thumbnail for publication 41
  33. “Cinchona Alkaloids as Organocatalysts in Enantioselective Halofunctionalization of Alkenes and Alkynes.”
    Zheng, S.; Schienebeck, C. M.; Zhang, W.; Wang, H.-Y.; Tang, W.* Asian J. Org. Chem. 2014, 3, 366-376. (Invited review) link.
    thumbnail for publication 40
  34. “Intermolecular bromoesterification of conjugated enynes: an efficient synthesis of bromoallenes.”
    Wang, H.-Y.; Zhang, W.; Schienebeck, C. M.; Bennett, S. R.; Tang, W.* Org. Chem. Front. 2014, 1, 386-390. (Invited contribution) link.
    thumbnail for publication 39
  35. “3-Acyloxy-1,4-enyne: a New Five-Carbon Synthon for Rhodium-Catalyzed [5 + 2] Cycloadditions.”
    Schienebeck, C. M.; Li, X.; Shu, X.-Z.; Tang, W.* Pure Appl. Chem. 2014, 86, 409-417. (Invited review) link.
  36. “Tethered Spectroscopic Probes Estimate Dynamic Distances with Subnanometer Resolution in Voltage-Dependent Potassium Channels.”
    Jarecki, B. W.; Zheng, S.; Zhang, L.; Li, X.; Zhou, X.; Cui, Q.; Tang, W.; Chanda, B.* Biophysical J. 2013, 105, 2724-2732. link.
    Highlight in Nature Chemical Biology link.
  37. “Rhodium-Catalyzed Tandem Annulation and (5+1) Cycloaddition: 3-Hydroxy-1,4-enyne as the 5-Carbon Component.”
    Li, X.; Song, W.; Tang, W.* J. Am. Chem. Soc. 2013, 135, 16797-16800. link.
    thumbnail for publication 35
  38. “Transfer of Chirality in the Rhodium-Catalyzed Intramolecular [5+2] Cycloaddition of 3-Acyloxy-1,4-Enynes (ACEs) and Alkynes: Synthesis of Enantioenriched Bicyclo[5.3.0]decatrienes.”
    Shu, X.-Z.; Schienebeck, C. M.; Song, W.; Guzei, I. A.; Tang, W.* Angew. Chem. Int. Ed. 2013, 52, 13601-13605. link.
    Highlight in Synfacts, 2014, volume 10, issue 3, 0295 (doi:10.1055/s-0033-1340687)
    thumbnail for publication 34
  39. “Stereoselective Halocyclization of Alkenes with N-Acyl Hemiaminal Nucleophiles.”
    Liu, N.; Wang, H.-Y.; Zhang, W.; Jia, Z.-H.; Guzei, I. A.; Xu, H.-D.;* Tang, W.* Chirality 2013, 25, 805-809. link.
    (Invited contribution.)
  40. “Stereoselective Total Synthesis of Hainanolidol and Harringtonolide via Oxidopyrylium-Based [5+2] Cycloaddition.”
    Zhang, M.; Liu, N.; Tang, W.* J. Am. Chem. Soc. 2013, 135, 12434-12438. link.
    thumbnail for publication 32
  41. “Platinum-Catalyzed Tandem Indole Annulation/Arylation for the Synthesis of Diindolylmethanes and Indolo[3,2-b]carbazoles.”
    Shu, D.; Winston-McPherson, G. N.; Song, W.; Tang, W.* Org. Lett. 2013, 15, 4162-4165. link.
    thumbnail for publication 31
  42. “Rh-Catalyzed (5+2) Cycloadditions of 3-Acyloxy-1,4-enynes and Alkynes: Computational Study of Mechanism, Reactivity, and Regioselectivity.”
    Xu, X.;* Liu, P.; Shu, X.-Z.; Tang, W.*; Houk, K. N.* J. Am. Chem. Soc. 2013, 135, 9271-9274. link.
    thumbnail for publication 30
  43. “Generation of Rhodium(I) Carbenes from Ynamides and Their Reactions with Alkynes and Alkenes.”
    Liu, R.; Winston-McPherson, G. N.; Yang, Z.-Y.; Zhou, X.; Song, W.; Guzei, I. A.; Xu, X.;* Tang, W.* J. Am. Chem. Soc. 2013, 135, 8201–8204. link.
    thumbnail for publication 29
  44. “Stereoselective Addition of Halogen to Conjugated Enynes and Its Application in the Total Synthesis of (-)-Kumausallene.”
    Werness, J. B.; Zhang, W.; Tang, W.* in Strategies and Tactics in Organic Synthesis
    Ed., Harmata, M., Elsevier Science, Pergamon Press: Oxford, UK 2013, Vol. 9, Chapter 10, pp 275-291.
  45. “Enantioselective intermolecular bromoesterification of allylic sulfonamides”
    Zhang, W.; Liu, N.; Schienebeck, C. M.; Zhou, X.; Izhar, I. I.; Guzei, I. A.; Tang, W.* Chem. Sci. 2013, 4, 2652-2656. link.
    thumbnail image of publication 27
  46. “Ring Expansion of Alkynyl Cyclopropanes to Highly Substituted Cyclobutenes via a N-Sulfonyl-1,2,3-Triazole Intermediate”
    Liu, R.; Zhang, M.; Winston-McPherson, G.; Tang, W.* Chem. Commun. 2013, 49, 4376-4378. link.
    (This article is part of the ChemComm ‘Emerging Investigators 2013’ themed issue.)
    thumbnail of publication 26
  47. “Effect of Ester on Rhodium-Catalyzed Intermolecular [5 + 2] Cycloaddition of 3-Acyloxy-1,4-enynes and Alkynes”
    Schienebeck, C. M.; Robichaux, P. J.; Li, X.; Chen, L.; Tang, W.* Chem. Commun. 2013, 49, 2616-2618. link.
    thumbnail for publication 25
  48. “Rhodium- and Platinum-catalyzed [4+3] Cycloaddition with Concomitant Indole Annulation: Synthesis of Cyclohepta[b]indoles”
    Shu, D.; Song, W.; Li, X.; Tang, W.* Angew. Chem. Int. Ed. 2013, 52, 3237-3240. link.
    thumbnail for publication 24
  49. “Rhodium-Catalyzed Chemo- and Regioselective Cross-Dimerization of Two Terminal Alkynes”
    Xu, H.-D.*; Zhang, R.-W.; Li, X., Huang, S., Tang, W.; Hu, W.-H. Org. Lett. 2013, 15, 840-843. link.
    thumbnail for publication 23