Month: June 2016

Targeted Treatment of FLT3-Overexpressing Acute Myelid Leukoemia with miR-150 Nanoparticles Guided by FLT3 Ligand Peptides

Posted on June 8, 2016

Abstract Acute myeloid leukemia (AML) is a common and fatal form of hematopoietic malignancy. Overexpression and/or mutations of FLT3 have been shown to occur in the majority of cases of AML. Our analysis of a large-scale AML …

Tuning Selectivity of Dendron Micelles through Variations of the PEG Corona

Posted on June 6, 2016

Abstract Engineering controllable cellular interactions into nanoscale drug delivery systems is key to enable their full potential. Here, using folic acid (FA) as a model targeting ligand and dendron micelles (DM) as a nanoparticle (NP) …