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AAPS Distinguished Seminar: Dr. Alita Miller

2006 Rennebohm Hall 777 Highland Ave, Madison, WI, United States

Antibiotic resistance is a serious public health crisis. Antibacterial regulatory guidelines have been recently updated to allow for more streamlined development of narrow-spectrum, precision therapies to treat highly problematic, multidrug-resistant bacterial infections

Pharm Sci Seminar – Jack Yalowich, PhD

1116 Rennebohm Hall 777 Highland Ave, Madison, WI, United States

DNA Topoisomerase IIα (TOP2α; 170 kDa) is a prominent target for anticancer drugs whose clinical efficacy is often compromised due to acquired chemoresistance.

Pharm Sci Seminar – Kirst King-Jones, PhD

1116 Rennebohm Hall 777 Highland Ave, Madison, WI, United States

We use the Drosophila prothoracic gland (PG) as a model to study tissues with high and dynamic demands in iron and heme.

2018 Busse Lecture (1 of 2): Simon J.L. Billinge, PhD

2006 Rennebohm Hall 777 Highland Ave, Madison, WI, United States

In the solid state, small molecules such as active pharmaceutical ingredient (API) molecules tend to pack in well defined arrangements leading to different crystalline polymorphs

2018 Busse Lecture (2 of 2): Simon J.L. Billinge, PhD

2006 Rennebohm Hall 777 Highland Ave, Madison, WI, United States

ncreasingly we seek smarter ways to deliver therapies in a targeted way. Nanoscience can play an important role in this endeavor

Pharm Sci Seminar – You Han Bae, PhD

1116 Rennebohm Hall 777 Highland Ave, Madison, WI, United States

Bile acids (BA) are biological surfactants synthesized in the liver and secreted to the duodenum via the gall bladder to help digest dietary fats.

Pharm Sci Seminar – Brian Shoichet, PhD

2006 Rennebohm Hall 777 Highland Ave, Madison, WI, United States

Molecular docking screens large compound libraries for molecules that complement a binding site, but do not resemble known ligands

Pharm Sci Seminar – Stephen Frye, PhD

2006 Rennebohm Hall 777 Highland Ave, Madison, WI, United States

Methyl-lysine (Kme) recognition domains play a central role in chromatin regulation during cellular differentiation, development, and gene transcription with more than 200 known Kme “reader” domains

Pharm Sci Seminar – Andy Wang, PhD

Signe Skott Cooper Hall 1227 701 Highland, Madison, WI, United States

This seminar will share our work on the development & clinical translation of nanotherapeutics in cancer chemoradiotherapy treatment, on recent work on applying nanotechnology to improve cancer immunotherapy, and the application of tissue engineering for cancer model development