September
23,
2022
(Drug DELIVERY Specific Seminar)
The global incidence of infections caused by bacteria and viruses has been increasing, which imposes a major threat to public health given the high morbidity and mortality rates associated with these diseases. Nanoparticle technology has enabled a wide array of improvements in the treatment of infectious diseases, ranging from improved efficacy in drug delivery to enhanced immunogenicity of vaccines. Among the different bio-inspired nanotechnology strategies, utilization of cellular membrane material for nanoparticle preparation presents a unique top-down approach that offers the advantage of being able to completely replicate the surface antigens and functions of source cells. Herein, I discuss the biological functionalization of polymeric nanoparticles with a layer of membrane coating derived from natural cells. Specifically, I will focus on the use of these cell-mimicking nanoparticles for the treatment of bacterial and viral infections.
Hosted by Seungpyo Hong
