2021 Louis Busse Lecture
- Aliasger K. Salem, PhD, FAAPS, FAIMBE
- University of Iowa
Biodegradable Particles for Vaccine Delivery
Antigen-loaded or antigen-coated biodegradable particles are capable of being actively taken up by antigen-presenting cells (APCs), and they have shown promising potential in immunotherapy by initiating a strong immunostimulatory cascade that results in potent antigen-specific immune responses against the target antigen. This lecture will show how such particle based carrier systems offer versatility because they can simultaneously co-deliver adjuvants with the antigens to enhance APC activation and maturation.
Hosted by Drug DELIVERY – Glen Kwon
Dr. Aliasger Salem is the Bighley Chair and Professor of Pharmaceutical Sciences at the University of Iowa College of Pharmacy. He received his PhD in pharmacy at the University of Nottingham, UK in 2002. He then received postdoctoral training at Johns Hopkins School of Medicine until 2004. His research interests are primarily focused on self-assembling systems, the rational design of novel drug and gene delivery systems, and on the development of vaccines that stimulate potent antigen-specific immune responses. He has a parallel program in the area of regenerative medicine.
The Busse Lecture Series is intended to bring speakers to the School of Pharmacy who have a fundamental research interest combined with a strong knowledge of the industrial pharmaceutical research environment.