Publications: 2018 – present

  1. “A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings”

    Zhao, C.; Ye, Z.; Ma, Z.-X.; Wildman, S. A.; Blaszczyk, S. A.; Hu, L.; Guizei, I. A.; Tang, W.* Nat. Commun. 2019, 10, 4015. Link.

  2. “Discovery of 2,3′-diindolylmethanes as a novel class of PCSK9 modulators”

    Winston-McPherson, G. N.; Xie, H.; Yang, K.; Li, X.; Shu, D.; Tang, W.* Bioorg. Med. Chem. Lett. 2019, 29, 2345-2348. Link. (Equal Contribution)

  3. “Development of Multi-Functional Histone Deacetylase 6 Degraders with Potent Anti-Myeloma Activity”

    Wu, H.; Yang, K.; Zhang, Z.; Leisten, E. D.; Li, Z.; Xie, H.; Liu, J.; Smith, K. A.; Novakova, Z.; Barinka, C.; and Tang, W.* J. Med. Chem. 2019, 62, 7042-7057. Link. (Equal Contribution)

  4. “Site‐ and Stereoselective Phosphoramidation of Carbohydrates Using a Chiral Catalyst and a Chiral Electrophile”

    Glazier, D. A.; Schroeder, J. M.; Blaszczyk, S. A.; Tang, W.* Adv. Syn. Cat. 2019, in press. Link.

  5. “Development of selective small molecule MDM2 degraders based on nutlin”

    Wang, B.;# Wu, S.;# Liu, J.; Yang, K.; Xie, H.; and Tang, W.* Eur. J. Med. Chem. 2019, 176, 476-491. Link.(#Equal Contribution)

    Image 1

  6. “S‐Adamantyl Group Directed Site‐Selective Acylation and Its Applications in the Streamlined Assembly of Oligosaccharides”

    Blaszczyk. S. A.;#  Xiao, G.;# Wen, P.;# Hao, H.; Wu, J.; Wang, B.; Carattino, F.; Li, Z.; Glazier, D. A.; McCarty, B. J.; Liu, P.* and Tang, W.* Angew. Chem. Int. Ed. 2019, 58, 9542-9546. Link. (#Equal Contribution)

  7. “Finding the Sweet Spot in SAX-ERLIC Mobile Phase for Simultaneous Enrichment of N-glyco and Phospho- peptides”

    Cui, Y.; Yang, K.; Tabang D. N.; Huang, J.; Tang, W., Li, L.* J. Am. Soc. Mass Spectrom. 2019, accepted.

  8. “Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models”

    Zhou, T.; Wang, Q.; Phan, N.; Ren, J.; Yang, H.; Feldman, C. C.; Feltenberger, J. B.; Ye, Z.; Wildman, S. A.; Tang, W., Liu, B.* Cell Death & Disease 2019, in press. Link.

  9. “Iridium-catalysed highly selective reduction-elimination of steroidal 4-en-3-ones to 3,5-dienes in water ”

    Li, J.; Tang, W.; Ren, D.; Xu, J.*; Yang, Y.*  Green Chem.  2019, 21, 2088-2094. Link.

  10. “Intermolecular Regio- and Stereoselective Hetero-[5+2] Cycloaddition of Oxidopyrylium Ylides and Cyclic Imines”

    Zhao, C.; Glazier, D. A.; Yang, D.; Yin, D.; Guzei, I. A.; Aristov, M. M.; Liu, P.* and Tang, W.* Angew. Chem. Int. Ed.  2019, 58, 887-891. Link.

  11. “Recent advances in site-selective functionalization of carbohydrates mediated by organocatalysts”

    Blaszczyk, S. A.; Homan, T. C.; Tang, W.* Carbohydrate. Res. 2019, 471, 64-77. Link.

  12. “Organocatalyst-Mediated Dynamic Kinetic Enantioselective Acylation of 2-Chromanols”

    Glazier, D. A.; Schroeder, J. M.; Liu, J.; Tang, W.* Adv. Syn. Cat. 2018, 360, 4646-4649. Link.

  13. “Iridium-Catalyzed Highly Efficient and Site-Selective Deoxygenation of Alcohols”

    Yang, S.; Tang. W.; Yang, Z.;* and Xu, J.* ACS Cat. 2018, 8, 9320-9326. Link.

  14. “Development of the first small molecule histone deacetylase 6 (HDAC6) degraders.”
    Yang, K.; Song, Y.; Xie, H.; Wu, H.; Wu, Y.-T.; Leisten, E. D.;  Tang W.* Bioorg. Med. Chem. Lett. 2018, 28, 2493-2497. link.
  15. “Catalytic Asymmetric Synthesis of All Possible Stereoisomers of 2,3,4,6‐Tetradeoxy‐4‐Aminohexopyranosides”

    Zhu Z.; Glazier, D. A.; Yang D.; Tang, W.* Adv. Syn. Cat. 2018, 360, 2211-2215. Link.

  16. “Iridium-catalyzed efficient reduction of ketones in water with formic acid as hydride donor at low catalyst loading”

    Liu, J.; Yang, S.; Tang, W.; Yang, Z.;* and Xu, J.* Green Chem. 2018, 20, 2118-2124. Link.

    Graphical abstract: Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading

  17. “Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR)”

    Seok, S.-H.; Ma, Z.-X.; Feltenberger, J. B.; Chen, H.; Chen, H.; Scarlett, C.; Lin, Z.; Satyshur, K. A.; Cortopassi, M.; Jefcoate, C. R.; Ge, Y.; Tang, W.; Bradfield, C. A.; and Xing, Y.* J. Biol. Chem. 2018, 293, 1994-2005. link.

  18. “Iridium-Catalyzed Dynamic Kinetic Stereoselective Allylic Etherification of Achmatowicz Rearrangement Products.”
    Zhu, Z.; Wang, H.-Y.; Simmons, C. J.; Tseng, P.-S.; Qiu, X.; Zhang, Y.; Duan, X.; Yang, J.-K.; and Tang W.* Adv. Syn. Cat. 2018, 360, 595-599. link.
  19. “Chiral Reagents in Glycosylation and Modification of Carbohydrates.”
    Wang, H.-Y.; Blaszczyk, S. A.; Xiao, G.; and Tang W.* Chem. Soc. Rev. 2018, 47, 681-701. link.