Program Faculty & Research

Pharmacology & Toxicology Faculty

Arash Bashirullah, PhD, Associate Professor
Regulation of tissue growth and destruction during post-embryonic development.
Ron Burnette, PhD, Professor
Developing a molecular level mechanistic understanding of the delivery and stability of drugs by physical chemical characterization of guest-host interactions using computational chemistry and NMR as well as studies in pharmacokinetics and pharmacodynamics.
Margaret Clagett-Dame, PhD, Professor
Therapeutic applications of vitamin A and vitamin D analogs; retinoids in embryonic and nervous system development.
Lara Collier, PhD, Associate Professor
Genetic and pharmacologic approaches to study cancer initiation, progression, and treatment.
Warren Heideman, PhD, Professor
Understanding the molecular mechanisms that regulate the cellular transition from quiescence to growth; identifying critical mechanisms regulating vertebrate development that are disrupted by environmental contaminants; evaluating the impact of nanomaterials on early development; creating strategies for the fermentative production of biofuels.
Jeffrey A. Johnson, PhD, Professor
Faculty Director of the Pharmacology-Toxicology Program
Signal transduction, transcriptional control of neuroprotective genes and neurotoxicity in Parkinson’s, Alzheimer’s, Huntington’s and Neuromuscular disease.
Paul C. Marker, PhD, Professor
Molecular basis of prostate development; prostate cancer progression; benign prostatic hyperplasia; roles of cell-cell signaling pathways and the use of mouse genetics to discover novel pathways that underlie prostatic diseases.
Steven G. Oakes, PhD, Clinical Assistant Professor

Affiliate Faculty

Ralph Albrecht, PhD, Professor
Use of inductively heated, antibody-targeted, core-shell nanoparticles for selective removal of targeted cells in vitro and in vivo. Developmenet of high resolution nanoparticle labeling systems for correlative microscopy.
Adnan Elfarra, PhD, Professor
Bioactivation and detoxification of drugs, industrial chemicals, and environmental toxicants; biochemical basis for target organ selectivity; and biomarkers of toxicant exposure.
Colin Jefcoate, PhD, Professor
Physiological Mechanisms Associated with P450 Cytochromes
Lauren Trepanier, PhD, DVM, Professor
Pharmacogenetics of xenobiotic toxicity, including both therapeutic drugs and environmental carcinogens. Mechanisms of familial and acquired risk for sulfamethoxazole drug hypersensitivity (“sulfa allergy”).  Examining the links between genetic variability in phase II detoxification pathways (GSTs and b5 reductase) and cancer risk in both humans and dogs.
Chad Vezina, Associate Professor
Molecular basis of prostate and urinary tract development, physiology, and toxicology.