Curriculum

Third Year (TOX-3)

Fall Semester
Course Name & Description Credits
Biochemistry 507 (General Biochemistry I) 3 cr.
Chemistry of biological materials, intermediary metabolism and protein structure. First semester of a year long first course in biochemistry.
Physiology 335 (Physiology [with lab]) 5 cr.
This course presents all of the major systems of the human body, providing a broad, integrated understanding of function from the cellular to the organ-system level.
Pharmaceutical Sciences 558 (Laboratory Techniques in Pharmacology & Toxicology) 2 cr.
Basic laboratory techniques employed in pharmacological and toxicological research.
Statistics* (one 3-4 credit statistics course is required during the program)
See below for course options
Electives**
Spring Semester
Course Name & Description Credits
Botany / Genetics / Zoology 466 (Principles of Genetics)*** 3 cr.
Genetics in eukaryotes and prokaryotes. Includes Mendelian genetics, mapping, molecular genetics, genetic engineering, cytogenetics, quantitative genetics, and population genetics. Illustrative material includes viruses, bacteria, plants, fungi, insects, and humans.
Biochemistry 508 (General Biochemistry II) 3 cr.
Chemistry of biological materials, intermediary metabolism and protein structure. Second semester of a year long first course in biochemistry.
Pathology 404 (Pathophysiologic Principles of Human Diseases) 3 cr.
Primarily for students of therapeutic sciences to provide a basic understanding of the causes, pathophysiology, pathology and clinical manifestations of disease states. Required course for occupational therapy and physical therapy students.
Pharmaceutical Sciences 679 (Pharmacology & Toxicology Seminar) 1 cr.
Senior student presentations of independent research or of published papers on a specific topic approved by the course coordinator. Faculty-led seminars on selected topics regarding responsible conduct of research. The course also provides a venue for career talks by Pharmacology-Toxicology alumni and guests working in a variety of professional settings – research, industry, and healthcare. Junior students participate via seminar observation, discussion, and construction of a written scientific research proposal.
Statistics* (one 3-4 credit statistics course is required during the program
See below for course options
Electives**
Genetics Curricular Option***

Fourth Year (TOX-4)

Fall Semester
Course Name & Description Credits
Pharmaceutical Sciences 521 (Pharmacology I) 3 cr.
Pharmacological actions of important drugs, including drugs that affect the peripheral nervous system, the central nervous system, and the gastrointestinal tract.
Pharmaceutical Sciences / Molecular & Environmental Toxicology 625 (Toxicology I) 3 cr.
Basic principles of toxicology and biochemical mechanisms of toxicity in mammalian species and man. Correlation between morphological and functional changes caused by toxicants in different organs of the body.
Biochemistry / Zoology 630 (Cellular Signal Transduction Mechanisms) OR Pharmaceutical Sciences 623 (Pharmacology III) 3 cr.
Comprehensive coverage of human hormones, growth factors and other mediators; emphasis on hormone action and biosynthesis, cell biology of hormone-producing cells.
Statistics* (one 3-4 credit statistics course is required during the program)
See below for course options
Electives**
Spring Semester
Course Name & Description Credits
Pharmaceutical Sciences 522 (Pharmacology II) 3 cr.
Pharmacological actions of important drugs, including hematopoietic, thrombolytic, antihyperlipidemic, immunopharmacologic, anticancer, anti-inflammatory, diuretic, antihypertensive, antianginal, and anti-arrhythmic agents, and agents used to treat congestive heart failure.
Pharmaceutical Sciences / Molecular & Environmental Toxicology 626 (Toxicology II) 3 cr.
A course surveying the basic methods and fundamental biochemical mechanisms of toxicity. Toxicity in mammalian organ systems, techniques for evaluating toxicity, as well as mechanisms of species specificity, and environmental interactions (with toxicant examples) are presented.
Pharmaceutical Sciences 679 (Pharmacology & Toxicology Seminar) 1 cr.
Senior student presentations of independent research or of published papers on a specific topic approved by the course coordinator. Faculty-led seminars on selected topics regarding responsible conduct of research. The course also provides a venue for career talks by Pharmacology-Toxicology alumni and guests working in a variety of professional settings – research, industry, and healthcare. Junior students participate via seminar observation, discussion, and construction of a written scientific research proposal.
Statistics* (one 3-4 credit statistics course is required during the program
See below for course options
Electives**

*Required Statistics Course, 3-4 cr. PharmTox students are required to take either Statistics 371, 3 cr. (Introductory Applied Statistics for the Life Sciences), Statistics 541, 3 cr. (Introduction to Biostatistics), OR Statistics 571, 4 cr. (Statistical Methods for Bioscience I) during the PharmTox program. The statistics requirement may be fulfilled in any semester of the program. Stat 371 is offered in the fall, spring, and summer semesters. Stat 541 is only offered in the fall and only fits the schedule of the PharmTox SENIOR year. Stat 571 is only offered in the fall and fits the schedule of the PharmTox JUNIOR or SENIOR year. Stat 541 or Stat 571 is recommended for those preparing for graduate study in the sciences. For more information comparing/contrasting these three statistics offerings, see the PharmTox academic advisor.

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** Electives consist of 5 credits of electives in the PharmTox major (see approved electives in the major list); any remaining non-major curriculum graduation requirements (i.e., Communications “B”, humanities, ethnic studies, second-semester general physics); and any free-choice electives needed to reach the required total of 120 degree credits.

Most Popular Electives in the Major
Bacteriology 303 (Biology of Microorganisms) 3 cr.
Molecular & Environmental Toxicology 606 (Colloquium in Environmental Toxicology) 1 cr.
Advanced Independent Study 699 (may be repeated) 1+ cr.
Anatomy 328 (Human Anatomy) Lectures. 3 cr.
Medical Microbiology & Immunology 528 (Immunology) 3 cr.

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***Advanced Independent Study (699) MUST be completed in either semester 1, 2, or 3 of the Pharm-Tox curricular sequence. 699 must be approved by Professor Jeff Johnson to meet Pharm-Tox major curriculum requirements. A web-lab basic science experience available in a variety of academic departments can fulfill the requirement.

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