Chemical Probe Development - Jiang Research Group

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Selected Publications:

1. Hu CW^#, Worth M^#, Fan D^#, Li B^#, Li H^#, Lu L, Zhong X, Lin Z, Wei L, Ge Y, Li L, Jiang J*. Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase. Nature Chemical Biology (2017) 13, 1267-73. (^#equal contribution).

abstract image for Jiang publication titled

2. Kositzke A^#, Fan D^#, Wang A, Li H, Worth M, Jiang J*. Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe. International Journal of Biological Macromolecules. (2021) 169, 51-59. doi: 10.1016/j.ijbiomac.2020.12.078. (#equal contribution).

3. Worth M^#, Hu CW^#, Li H, Fan D, Estevez A, Zhu D, Wang A, Jiang J*. Targeted covalent inhibition of O-GlcNAc transferase in cells. Chemical Communications (2019) 55, 13291-4. (#equal contribution).