Hong Research Group
127. “Fibronectin-targeting Dendron Micelles Effectively Deliver BRD4 Inhibitors for Inflammation Reduction in an Idiopathic Pulmonary Fibrosis Model” C.M. Hopkins, J.W. Lee, M. Skibba, Z. Ma, K. Bernau, N. Mamidi, N. Sandbo, J. Zhou, A.R. Brasier*, and S. Hong*, 2024, Submitted.
126. “Recent Advances in HIV therapeutics: New Horizons in HIV Treatment” Y. Jang, A. Vasukutty, S.H. Kang, S. Hong, H.W. Seo, B.S. Choi, K.C. Kim, W.J. Kim, I.K. Park, and H. Park*, Archives of Pharmacal Research, 2024, In Revision.
125. “Diagnostic Proflie of CapioCyte – Highly Sensitive Circulating Tumor Cell Capture Technology” M.J. Poellmann, J. Bu, A.Z. Wang, K.C. Nam and S. Hong *, Expert Review of Molecular Diagnostics, 2024, In Revision.
124. “Dendrimer conjugates with PD-L1-binding peptides enhance in vivo anti-tumor immune response” D. Kim, P. A. Rawding, M. Iida, J. Lee, K. L. Kostecki, M. J. Poellmann, B. Mehall, D. L. Wheeler*, and S. Hong*, Advanced Healthcare Materials, 2024, In Revision.
123. “Multifunctional Dendrimer-Peptide Conjugates for MET Receptor-specific Imaging of Cancer Cells” J. Lee, K. P. Nickel, R. Minne, J. J. Jeffery, E. Aluicio-Sarduy, C. Kim, D. Kim, P. A. Rawding, M. J. Poellmann, N. Mamidi, J. Engle, J. H. Lee, R. Hernandez, R. J. Kimple, A. M. Baschnagel, and S. Hong*, Nano Today, 2024, In Revision.
122. “Innovative Hydrogel-Based Delivery Systems for Immunotherapy: A Review of Pre-Clinical Progress” N. Mamidi, M. Poellmann, K. Javius-Jones, K. Nam, and S. Hong*, Nano Research, 2024, In Revision.
121. “Tumor cells gain competitive advantage by actively reducingthe cellular fitness of microenvironment cells” E. Madan, A. M. Palma, V. Vudatha, A. Kumar, P. Bhoopathi, J. Wilhelm, T. Bernas, P. C. Martin, G. Bilolikar, H. Kim, A. Gogna, M. L. Peixoto, I. Dreier, T. F. Araujo, K. Dorayappan, D. Oh, N. Mamidi, Z. Su, M. Yekelchyk, D. Accardi, G. Xiao, A. L. Olsen, L. Lin, A. A. Titelman, M. Bianchi, P. Jessmon, E. A. Farid, A. Pradhan, L. Neufeld, S. Maji, C. J. Pelham, E. Yeini, E. Garre, A. Gustafsson, H. O. Rolfsnes, R. C. Marques, A. Lu, M. Nagane, K. G. Achary, J. Akhtar, S. Belião, L. Liao, K. Bhoopathi, P. Mannangatti, S. Das, A. Bigio, I. Correia, C. L. da Silva, A. M. Fialho, M. J. Poellmann, K. Javius-Jones, A. M. Hawkridge, S. Pal, K. S. Shree, S. Khurana, D. Zhang, U. Menon, A. Sanyal, A. S. Poklepovic, C. Lyons, S. R. Grossman, D. P. Turner, G. L. Robinson, R. Pillappa, J. Koblinski, G. Gupta, K. Selvendiran, G. Singh, S. Singh, A. Tsung, K. Prakash, S. Rayamajhi, M. D. Bacolod, H. Richards, S. Sayeed, K. P. Klein, R. Satchi-Fainaro, D. Connolly, F. A. Thorsen, R. Bjerkvig, K. P. Nephew, M. Idowu, M. P. Kühnel, C. Moskaluk, S. Hong, W. L. Redmond, G. Landberg, A. Lopez-Beltran, D. Chelmow, P. B. Fisher, G. M. Church, R. Drapkin, A. K. Godwin, Y. Luo, A. Tzankov, K. D. Mertz, M. Ackermann, D. Jonigk, D. Sidransky, A. P. Saavedra, R. Winn, J. Trevino, K. J. Won, E. Moreno, R. Gogna*, Nature Biotechnology, 2024, Accepted.
120. “Normothermic Liver Perfusion Derived Extracellular Vesicles Have Concentration-Dependent Immunoregulatory Properties” H. Jennings, S. McMorrow, P. Chlebeck, G. Heise, M. Levitsky, B. Verhoven, J.A. Kink, K. Weinstein, S. Hong, and D.P. Al-Adra, Journal of Extracellular Vesicles, 2024, 13(7):e12485.
119. “Dendritic Nanoparticles for Immune Modulation: A potential next-generation nanocarrier for cancer immunotherapy” D. Kim‡, K. Javius-Jones‡, N. Mamidi, and S. Hong*, Nanoscale, 2024, 16:10208-10220.
118. “Prospective Characterization of Circulating Tumor Cell Kinetics in Patients With Oligometastatic Disease Receiving Definitive Intent Radiation Therapy” S. Sud‡, M.J. Poellmann‡, J. Hall, X. Tan, J. Bu, J.H. Myung, S.-J. Park, A.Z. Wang, S. Hong*, and D. Casey*, Journal of Clinical Oncology (JCO) Precision Oncology, 2023, e2300303.
117. “Carprofen alleviates Alzheimer-like phenotypes of 5XFAD transgenic mice by targeting the pathological hallmarks induced by amyloid-β aggregation” D. Lee, J.E. Ryoo, S. Hong, H.Y. Kim, and Y.S. Kim*, Scientific Reports, 2023, 13(1):10889.
116. “Circulating tumor cell abundance in head and neck squamous cell carcinoma decreases with successful chemoradiation and cetuximab treatment” M.J. Poellmann, J. Bu, D. Kim, M. Iida, H. Hong, A. Wang, D.L. Wheeler, R. Kimple, and S. Hong*, Cancer Letters, 2023, 562:216187.
115. “Extracellular Vesicle-Associated GARP/TGFβ:LAP Mediates “Infectious” Allo-Tolerance” W.J. Burlingham, E. Jankowska-Gan, J.H. Fechner, C.J. Little, J. Wang, S. Hong, M. Molla, J.A. Sullivan, and D.P. Foley*, Transplantation Direct, 2023, 9(6):e1475.
114. “Structurally Engineered Silica Shells on Gold Nanorods for Biomedical Applications” M.J. Kim, D.H. Jung, C.Y. Lee, S. Hong*, J.H. Heo*, and J.H. Lee*, Small Structures, 2023, 2300047.
113. “A Hybrid Nanoparticle System Integrating Tumor-derived Exosomes and Poly(amidoamine) Dendrimers: Implication for an effective gene delivery platform” A. Nair‡, K. Javius-Jones‡, J. Bugno, M.J. Poellmann, N. Mamidi, I.-S. Kim, I.C. Kwon, H. Hong, and S. Hong*, Chemistry of Materials, 2023, 35(8), 3138–3150.
112. “Dual Axl/MerTK Inhibitor INCB081776 Creates a Proinflammatory Tumor Immune Microenvironment and Enhances Anti-PDL1 Efficacy in Head and Neck Cancer” K.L. Kostecki, M. Iida, A.L. Wiley, S. Kimani, B. Mehall, K. Tetreault, R. Alexandridis, M. Yu, S. Hong, R. Salgia, J.Y. Bruce, R.B. Birge, P.M. Harari, and D.L. Wheeler*, Head & Neck, 2023, e27340.
111. “Nanotechnology and Machine Learning Enable Circulating Tumor Cells as a Reliable Biomarker for Radiotherapy Responses of Gastrointestinal Cancer Patients” M.J. Poellmann, J. Bu, S. Liu, A.Z. Wang, S.N. Seyedin, C. Chandrasekharan, H. Hong, J.M. Caster, and S. Hong*, Biosensors and Bioelectronics, 2023, 226:115117.
110. “Cell-Based Drug Delivery Systems with Innate Homing Capability as a Novel Nanocarrier Platform” A. Choi‡, K. Javius-Jones‡, S. Hong*, and H. Park*, International Journal of Nanomedicine, 2023, 18, 509—525.
109. “Dendrimer-Peptide Coinjugates for Effective Blockade of the Interactions betweeen SARS-CoV-2 Spike Protein and Human ACE2 Recpetor” W.j. Jeong, J. Bu, P. Mickel, Y. Han, P.A. Rawding, J. Wang, H. Hong*, P. Kral*, and S. Hong*, Biomacromolecules, 2023, 24(1), 141-149.
108. “Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL” K. Gupta, K.A. Brown, M.L. Hsieh, B.M. Hoover, J. Wang, M.K. Khoury, V.S.S. Pilli, R.S.H. Beyer, N.R. Voruganti, S. Chaudhary, D.S. Roberts, R.M. Murphy, S. Hong, Y. Ge, and B. Liu*, Journal of Extracellular Vesicles, 2022, 11(9):e12261.
107. “Bimodal Liquid Biopsy for Cancer Immunotherapy Based on Peptide Engineering and Nanoscale Analysis” J. Bu, W.-j. Jeong, L.J. Kubiatowicz, A. Nair, A.J. Drelich, M.J. Poellmann, R.S. Hong, E.W. Liu, R.H. Own, D.J. George, A.J. Armstrong, A.Z. Wang, J. Bruce, T. Zhang, R.J. Kimple, and S. Hong*, Biosensors and Bioelectronics, 2022, 213:114445.
106. “Combination of Chemo-, Immuno-, and Gene Therapies Using Nanocarriers As A Multifunctional Drug Platform” C. Hopkins, K. Javius-Jones, Y. Wang, Q. Hu*, and S. Hong *, Expert Opinion on Drug Delivery, 2022, 19(10), 1337.
105. “Physiological Roles of Monomeric Amyloid-β and Implications for Alzheimer’s Disease Therapeutics” H. Jeong, H. Shin, S. Hong*, and Y. Kim*, Experimental Neurobiology, 2022, 30;31(2):65-88.
104. “Dendritic-Linear Copolymer and Dendron Lipid Nanoparticles for Drug and Gene Delivery” M.J. Poellmann, K. Javius-Jones, C. Hopkins, J.W. Lee, and S. Hong*, Bioconjugate Chemistry, 2022, 33, 11, 2008–2017.
103. “Machine-Learning-Based Clinical Biomarker Using Cell-Free DNA for Hepatocellular Carcinoma (HCC)” T.H. Lee, P.A. Rawding, J. Bu, S. Hyun, W.S. Rou, H.J. Jeon, S.H. Kim, B.S. Lee, L.J. Kubiatowicz, D.W. Kim, S. Hong*, and H.S. Eun*, Cancers, 2022, 14(9), 2061.
102. “AXL Regulates Neuregulin1 Expression Leading to Cetuimab Resistance in Head and Neck Cancer” M. Iida, N.K. McKaniel, K.L. Kostecki, N.B. Welke, C.A. Kranjac, P. Liu, C. Longhurst, J.Y. Bruce, S. Hong, R. Salgia, and D.L. Wheeler*, BMC Cancer, 2022, 22(1), 447.
101. “Depletion of Tumor Associated Macrophages Enhances Local and Systemic Platelet-mediated Anti-PD-1 Delivery for Post-surgery Tumor Recurrence Treatment” Z. Li, Y. Ding, J. Liu, J. Wang, F. Mo, Y. Wang, T.J. Chen-Mayfield, P.M. Sondel, S. Hong, Q. Hu*, Nature Communications, 2022, 13(1), 1845.
100. “Cross-Decoration of Dendritic Cells by Non-Inherited Maternal Antigen-Containing Extracellular Vesicles: Potential Mechanism for PD-L1-Based Tolerance in Cord Blood and Organ Transplantation” D.A. Lema, E. Jankowska-Gan, A. Nair, S.B. Kanaan, C.J. Little, D.P. Foley, A.R. Naqvi, J. Wang, S. Hong, J.L. Nelson, D. Al-Adra, W.J. Burlingham, and J.A. Sullivan*, American Journal of Transplantation, 2022, 22(5), 1329-1338.
99. “Gold Nanoparticles in Virus Detection: Recent Advances and Potential Considerations for COVID-19 Diagnostics Development” J. Wang, A.J. Drelich, C.M. Hopkins, S. Mecozzi, L. Li, G. Kwon, and S. Hong*, WIREs Nanomedicine & Nanobiotechnology, 2022, 14(1), e1754.
98. “Branched, Dendritic, and Hyperbranched Polymers in Liquid Biopsy Device Design” M.J. Poellmann, P. Rawding, D. Kim, J. Bu, Y. Kim, and S. Hong*, WIREs Nanomedicine & Nanobiotechnology, 2022, e1770.
97.“Native Ion Mobility-Mass Spectrometry-Enabled Fast Structural Interrogation of Labile Protein Surface Modifications at the Intact Protein Level” G. Li, A. Phetsanthad, M. Ma, Q. Yu, A. Nair, Z. Zheng, K. DeLaney, F. Ma, S. Hong, and L. Li*, Analytical Chemistry, 2022, 94(4), 2142-2153.
96. “Hierarchically Multivalent Peptide-Nanoparticle Archtectures: A systematic approach to engineer surface adhesion” W.-j. Jeong, J. Bu, R. Jafari, P. Rehak, L.J. Kubiatowicz, A.J. Drelich, R.H. Owen, A. Nair, P.A. Rawding, M.J. Poellmann, C.M. Hopkins, and S. Hong*, Advanced Science, 2022, 9(4), e2103098.
95. “Cytochalasin B Treatment and Osmotic Pressure Enhance the Production of Extracellular Vesicles (EVs) with Improved Drug Loading Capacity” A. Nair, J. Bu, P.A. Rawding, S.C. Do, H. Li, and S. Hong*, Nanomaterials, 2022, 12 (1), 3
94. “Dendrimers for Cancer Immunotherapy: Avidity-based drug delivery vehicles for effective anti-tumor immune response” P.A. Rawding, J. Bu, J. Wang, D.W. Kim, A.J. Drelich, Y. Kim, and S. Hong*, WIREs Nanomedicine Nanobiotechnology, 2021, e1752
93. “Size-dependent Drug Loading, Gene Complexation, Cell Uptake, and Transfection of a Novel Dendron-Lipid Nanoparticle for Drug/Gene Co-delivery” A. Nair, J. Bu, J. Bugno, P.A. Rawding, L.J. Kubiatowicz, W.-j. Jeong, and S. Hong*, Biomacromolecules, 2021, 22(9), 3746–3755
92. “Tri-modal Liquid Biopsy: Combinational analysis of circulating tumor cells, exosomes, and cell-free DNA using machine learning algorithm” J. Bu, T. H. Lee, M.J. Poellmann, P.A. Rawding, W.-j. Jeong, R.S. Hong, S.H. Hyun, H.S. Eun, and S. Hong*, Clinical and Translational Medicine, 2021, 11(8), e499
91. “Chemically and biologically engineered bacteria-based delivery systems for emerging diagnosis and advanced therapy” Z. Li, Y. Wang, J. Liu, P.A. Rawding, J. Bu, S. Hong, and Q. Hu*, Advanced Materials, 2021, 33, 2102580
90. “Orally Administered Benzofuran Derivative Disaggregated ABeat Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse” D. Kim, G.H. Bae, H.Y. Kim, H. Jeon, K. Kim, J. Shin, S. Lee, S. Hong, I. Kim, and Y.S. Kim, ACS Chemical Neuroscience, 2021, 12(1), 99-108
89. “Nanoapproaches to modifying epigenetics of EMT for treatment of pulmonary fibrosis” M. Skibba, A. Drelich, M. Poellmann, S. Hong*, and A.R. Brasier*, Frontiers in Pharmacology, 2020, 11, 607689
88. “Enhanced Detection of Cell-free DNA Enables Its Use as a Reliable Biomarker for Diagnosis and Prognosis of Advanced Gastric Cancer” J. Bu, T.H. Lee W.-j. Jeong, M.J. Poellmann, K. Mudd, H.S. Eun, E.W. Liu, S. Hong*, and S.H. Hyun*, PLoS ONE, 2020, 15(12), e0242145
87. “An Avidity-based PD-L1 Antagonist Using Nanoparticle-Antibody Conjugates for Enhanced Immunotherapy” J. Bu, A. Nair, M. Iida, W.-j. Jeong, M.J. Poellmann, K. Mudd, L.J. Kubiatowicz, E.W. Liu, D.L. Wheeler, and S. Hong*, Nano Letters, 2020, 20(7), 4901-4909
86. “Immunoavidity-Based Capture of Tumor Exosomes Using Poly(amidoamine) Dendrimer Surfaces” M.J. Poellmann, A. Nair, J. Bu, J.K.H. Kim, R.J. Kimple, and S. Hong*, Nano Letters, 2020, 20(8), 5686-5692
85. “AXL mediates cetuximab and radiation resistance through tyrosine 821 and the c-ABL kinase pathway in head and neck cancer” N.K. McDaniel, M. Iida, K.P. Nickel, C.A. Longhurst, S.R. Fischbach, T. Rodems, C.A. Kranjac, A.Y. Bo, Q. Luo, M.M. Gallagher, N.B. Welke, K.R. Mitchell, A.E. Schulz, J.C. Eckers, R. Hu, R. Salgia, S. Hong, J.Y. Bruce, R.J. Kimple, and D.L. Wheeler*, Clinical Cancer Research, 2020, 26, 4349-4359
84. “Surface Engineering for Efficient Capture of Circulating Tumor Cells in Renal Cell Carcinoma: From nanoscale analysis to clinical application” J. Bu, A. Nair, L.J. Kubiatowicz, M.J. Poellmann, W.-j. Jeong, M. Reyes-Martinez, A.J. Armstrong, D.J. George, A.Z. Wang, T. Zhang, and S. Hong*, Biosensors and Bioelectronics, 2020, 162, 112250
83. “Surface Functionalization of Dual Growth Factor on Hydroxyapatite-Coated Nanofibers for Bone Tissue Engineering” N. Udomluck, H. Lee, S. Hong, S.-h. Lee*, and H. Park*, Applied Surface Science, 2020, 520(1), 146311
82. “Alzheimer’s Disease Diagnosis Using Misfolding Proteins in Blood” Lee H, Ugay D, Hong S*, Kim Y. Dement Neurocogn Disord. 2020 Jan;19:e5.
81. “Treg-Derived IL35-Coated Extracellular Vesicles Promote Infectious Tolerance” J.A. Sullivan, Y. Tomita, E. Jankowska-Gan, D. Lema, M. Arvedson, A. Nair, W. Bracamonte-Baran, Y. Zhou, D.V. Sawant, A.L. Szymczak-Workman, Q. Zhang, C.J. Workman, S. Hong, D.A.A. Vignali, and W.J. Burlingham*, Cell Reports, 2020, 30(4), 1039-1051.
80. “Nanoparticle Conjugation Stabilizes and Multimerizes β-Hairpin Peptides to Effectively Target PD-1/PD-L1 β-Sheet-Rich Interfaces” W.-j. Jeong, J. Bu, Y. Han, A.J. Drelich, A. Nair, P. Kral, and S. Hong*, Journal of the American Chemical Society, 2020, 142(4), 1832-1837.
79. “Diagnosis of Alzheimer’s disease utilizing amyloid and tau as fluid biomarkers” J.C. Lee, S.J. Kim, S. Hong, and Y. Kim*, Exp. Mol. Med. 2019, 51(5), 53.
78. “Sub-lethal hyperthermia promotes epithelial-to-mesenchymal-like transition of breast cancer cells: implication of the synergy between hyperthermia and chemotherapy” T.H. Lee, J. Bu, B.H. Kim, M.J. Poellmann, S. Hong*, and S.H. Hyun*, RSC Advances, 2019, 9(1), 52-57.
77. “Tumor Penetration of Sub-10 nm Nanoparticles: Effect of Dendrimer Properties on Their Penetration in Multicellular Tumor Spheroids” J. Bugno, M.J. Poellmann, K. Sokolowski, H.-j. Hsu, D.H. Kim, and S. Hong*, Nanomedicine: Nanotechnology, Biology and Medicine 2019, 21, 102059
76. “A Dendrimer-based Platform for Effective Capture of Tumor Cells after TGFβ1-induced Epithelial-Mesenchymal Transition” J.H. Myung, A. Cha, K.A. Tam, M.J. Poellmann, A. Borgeat, R. Sharifi, E.M. Robert, V.-v. Gina, and S. Hong*, Analytical Chemistry, 2019, 91(13), 8374-8382
75. “Dendritic PEG Outer Shells Enhance Serum Stability of Polymeric Micelles” H.-j. Hsu, Y. Han, M. Cheong, P. Kral, and S. Hong*, Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(6), 1879-1889.
74. “Multivalent Binding and Biomimetic Cell Rolling Improves the Sensitivity and Specificity of Circulating Tumor Cell (CTC) Capture” J.H. Myung, M.J. Eblan, J.M. Caster, K. Wang, S.-j. Park, K.A. Tam, S.M. Miller, R.L. Green, R.C. Chen, J.E. Tepper, B.S. Chera, A.Z. Wang*, and S. Hong*, Clinical Cancer Research, 2018, 24(11), 2539-2547.
73. “Non-catalytic Endosialidase Enables Surface Capture of Small-cell Lung Cancer Cells Utilizing Strong Dendrimer-mediated Enzyme-Glycoprotein Interactions” H.-j. Hsu, H. Palka-Hamblin, G.P. Bhide, J.H. Myung, M. Cheong, K.J. Colley, and S. Hong*, Analytical Chemistry, 2018, 90(6), 3670-3675.
72. “Bespoke Pretargeted Nanoradioimmunotherapy for the Treatment of Non-Hodgkin Lymphoma” K.M. Au, A. Tripathy, C.P. Lin, S. Hong, A.Z. Wang, S.I. Park, ACS Nano, 2018, 12(2), 1544-1563.
71. “Nanotechnology enabling the use of circulating tumor cells (CTCs) as reliable cancer biomarkers.” S. Hong, A.Z. Wang, Advanced Drug Delivery Reviews, 2018, 125, 1-2.
70. “Integration of Biomimicry and Nanotechnology for Significantly Improved Detection of Circulating Tumor Cells (CTCs)” J.H. Myung, S.-J. Park, A.Z. Wang, S. Hong*, Advanced Drug Delivery Reviews, 2018, 125, 36-47.
69. “Clinical Indications for, and the Future of, Circulating Tumor Cells” D. Moon, S. Hong, A.Z. Wang*, Advanced Drug Delivery Reviews, 2018, 125, 143-150.
68. “Would antioxidant-loaded nanoparticles present an effective treatment for ischemic stroke?” M.J. Poellmann, J. Bu, S. Hong*, Nanomedicine, 2018, 13, 2327-2340.
67. “Peptide–nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms?” W.-J. Jeong, J. Bu, L.J. Kubiatowicz, S.S. Chen, Y. Kim, and S. Hong*, Nano Convergence, 2018, 5, 38
66. “Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer” M. Kawakami, L.M. Mustachio, J. Rodriguez-Canales, B. Mino, J. Roszik, P. Tong, J. Wang, J.J. Lee, J.H. Myung, J.V. Heymach, F.M. Johnson, S. Hong, L. Zheng, S. Hu, P.A. Villalobos, C. Behrens, I. Wistuba, S. Freemantle, X. Liu, and E. Dmitrovsky*, Journal of the National Cancer Institute, 2017, 109(6), djw297
65. “Chemical Structure and Surface Modification of Dendritic Nanomaterials Tailored for Therapeutic and Diagnostic Applications” J.H. Myung, H.-j. Hsu, J. Bugno, K.A. Tam, and S. Hong*, Current Topics in Medicinal Chemistry, 2017, 17(13), 1542 – 1554.
64. “Dendrimer-Based Nanocarriers: A Versatile Platform for Drug Delivery” H.-j. Hsu, J. Bugno, S.-r. Lee, and S. Hong*, WIREs Nanomedicine Nanobiotechnology 2017, 9(1), e1409.
63. “Targeted Treatment of FLT3-overexpressing Acute Myeloid Leukemia with miR-150 Nanoparticles guided by FLT3 Ligand Peptides” X. Jiang, J. Bugno, C. Hu, Y. Yang, T. Herold, J. Qi, P. Chen, S. Gurbuxani, S. Arnovitz, B. Ulrich, H. Weng, Y. Wang, H. Huang, S. Li, J. Strong, M.B, Neilly, R.A. Larson, M.M. Le Beau, S.K. Bohlander, J. Jin, Z. Li, J.E. Bradner, S. Hong*, and J. Chen*, Cancer Research 2016, 76(15), 4470-4480.
62. “Tuning the Selectivity of Dendron Micelles through Variations of the PEG Corona” R.M. Pearson, S. Sen, H.-j. Hsu, M. Pasko, M. Gaske, P. Kral, and S. Hong*, ACS Nano 2016, 10(7), 6905-6914.
61. “Size and Surface Charge of Engineered Poly(amidoamine) Dendrimers Modulate Tumor Accumulation and Penetration: A model study using multicellular tumor spheroids” J. Bugno, H.-j. Hsu, R.M. Pearson, H. Noh, and S. Hong*, Molecular Pharmaceutics 2016, 13(7), 2155-2163.
60. “Biomimetic 3D Clusters using Human Adipose Derived Mesenchymal Stem Cells and Breast Cancer Cells: A study on migration and invasion of breast cancer cells” M.H. Park, B. Song, S. Hong, K. Lee*, and S.-H. Kim*, Molecular Pharmaceutics 2016, 13(7), 2204-2213.
59. “miR-22 Has a Potent Anit-Tumour Role with Therapeutic Potential in Acute Myeloid Leukemia” X. Jiang, C. Hu, S. Arnovitz, J. Bugno, M. Yu, Z. Zuo, P. Chen, H. Huang, B. Ulrich, C. Hu, S. Gurbuxani, H. Weng, J. Strong, Y. Wang, Y. Li, J. Salat, S. Li, A.G. Elkahloun, Y. Yang, M.B. Neilly, R.A. Larson, M.M. Le Beau, T. Herold, S.K. Bohlander, P.P. Liu, J. Zhang, Z. Li, C. He, J. Jin, S. Hong, and J. Chen*, Nature Communications 2016, 7, 11452.
58. “Recent Advances in Nanotechnology-based Detection and Separation of Circulating Tumor Cells” J.H. Myung, K.A. Tam, S.-j. Park, A. Cha, and S. Hong*, WIREs Nanomedicine & Nanobiotechnology 2016, 8(2), 223-239.
57. “Single Plasmonic Nanoparticles for Ultrasensitive DNA Sensing: From invisible to visible” L. Guo, L. Chen, S. Hong*, and D.-H. Kim*, Biosensors and Bioelectronics 2016, 79, 266-272.
56. “Microfluidic Devices to Enrich and Isolate Circulating Tumor Cells” J.H. Myung and S. Hong*, Lab on a Chip 2015, 15, 4500-4511.
55. “Effective Capture of Circulating Tumor Cells from a Transgenic Mouse Lung Cancer Model using Dendrimer Surfaces Immobilized with anti-EGFR” J.H. Myung, M. Roengvoraphoj, K.A. Tam, T. Ma, V.A. Memoli, E. Dmitrovsky, S.J. Freemantle, and S. Hong*, Analytical Chemistry 2015, 87(19), 10096-100102.
54. “Tweaking Dendrimers and Dendritic Nanoparticles for Controlled Nano-bio Interactions: Potential Nanocarriers for Improved Cancer Targeting” J. Bugno, H.-J. Hsu, and S. Hong*, Journal of Drug Targeting 2015, 23(7-8), 642-650. Invited Review for a special issue honoring Robert Langer.
53. “The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo” W. Gao, J.-Y. Kim, J. Anderson, T. Akopian, S. Hong Y.-Y. Jin, O. Kandror, J.-W. Kim, I.-He. Lee, S. Lee, J. McAlpine, S. Mulugeta, S. Sunoqrot, Y. Wang, S. Yang, T. Yoon, A. Goldberg, G. Pauli, J. Suh, S. Ranzblau, and S. Cho, Antimicrobial Agents and Chemotherapy 2015,59(2), 880-889.
52. “Recent Advances in Targeted Drug Delivery Approaches Using Dendritic Polymers” J. Bugno, H.-j. Hsu, and S. Hong*, Biomaterials Science 2015, 3(7), 1025-1034.
51. “Biomolecular Corona on Nanoparticles: A survey of recent literature and its implications in targeted drug delivery” R.M. Pearon, V.V. Juettner, and S. Hong*, Frontiers in Chemistry 2014, 2, 108, 1-7.
50. “Poly(ethylene glycol) Corona Chain Length Controls End-Group-Dependent Cell Interactions of Dendron Micelles” H.-j. Hsu, S. Sen, R.M. Pearson, S. Uddin, P. Kral, and S. Hong*, Macromolecules 2014, 47, 6911-6918.
49. “Differential Detection of Tumor Cells using A Combination of Cell Rolling, Multivalent Binding, and Multiple Antibodies” J.H. Myung, K.A. Gajjar, J. Chen, R.E. Molokie, and S. Hong*, Analytical Chemistry 2014, 86(12), 6088-6094.
48. “Prolonged Blood Circulation and Enhanced Tumor Accumulation of Folate-Targeted Dendrimer-Polymer Hybrid Nanoparticles” S. Sunoqrot, J. Bugno, D. Lantvit, J.E. Burdette, and S. Hong*, Journal of Controlled Release 2014, 191, 115-122.
47. “Understanding Nano-Bio Interactions to Improve Nanocarriers for Drug Delivery” R.M. Pearon, H.-J. Hsu, J. Bugno, and S. Hong*, MRS Bulletin 2014, 39 (3), 227-237.
46. “Targeting of Follicle Stimulating Hormone Peptide-Conjugated Dendrimers to Ovarian Cancer Cells” D.A. Modi, S. Sunoqrot, J. Bugno, D.D. Lantvit, S. Hong*, and J.E. Burdette*, Nanoscale 2014, 6, 2812-2820.
45. “Dendron-based Micelles for Topical Delivery of Endoxifen: A potential chemo-preventive medicine for breast cancer” Y. Yang, R.M. Pearson, O. Lee, C.-W. Lee, R.T. Chatterton, S.A. Khan, and S. Hong*, Advanced Functional Materials 2014, 24(17), 2441-2449.
44. “Epithelia-Mesenchymal Transition Enhances Nano-scale Actin Filament Dynamics of Ovarian Cancer Cells” S. Lee, Y. Yang, D. Fishman, M.M. Banaszak Holl, and S. Hong*, Journal of Physical Chemistry B 2013, 117(31), 9233-9240.
43. “Sustained Release of Matrix Metalloproteinase-3 to Trabecular Meshwork Cells using Biodegradable PLGA Microparticles” S. Turturro, S. Sunoqrot, H. Ying, S. Hong*, and B.Y.J.T. Yue*, Molecular Pharmaceutics 2013, 10(8), 3023-3032.
42. “Solid-Phase Colorimeteric Sensor Based on Gold Nanoparticle-loaded Polymer Brushes: Lead Detection as a Case Study” A.R. Ferhan, L. Guo, X. Zhou, P. Chen, S. Hong, and D.H. Kim*, Analytical Chemistry 2013, 85(8), 4094-4099.
41. “Nanoscale Polymeric Penetration Enhancers for Topical Drug Delivery” Y. Yang, J. Bugno, and S. Hong*, Polymer Chemistry 2013, 4, 2651-2657.
40. “Positively Charged Dendron Micelles Display Negligible Cellular Interactions” R.M. Pearson, N. Patra, H.-J. Hsu, S. Uddin, P. Kral, and S. Hong*, ACS Macro Letters 2013, 2, 77-81.
39. “In Vitro Evaluation of Dendrimer-Polymer Hybrid Nanoparticles on Their Controlled Cellular Targeting Kinetics” S. Sunoqrot, Y. Liu, D.H. Kim, and S. Hong*, Molecular Pharmaceutics 2013, 10(6), 2157-2166.
38. “Distance-mediated Plasmonic Dimers for Reusable Colorimetric Switches: A Measurable Peak Shift of Over 60 nm” L. Guo, R.A. Ferhan, H.L. Chen, C. Li, G. Chen, S. Hong, and D.H. Kim*, Small 2013, 9(2), 233-240.
37. “Enhanced Oral Bioavailability of the Hydrophobic Chemopreventive Agent (SR13668) in Beagle Dogs” A.A. Banerjee, H. Shen, M. Hautman, J. Anwer, S. Hong, I.M. Kapetanovic, A.V. Lyubimov, and Y. Liu*, Current Pharmaceutical Biotechnology 2013, 14(4), 464-469.
36. “Nanotechnology in Corneal Neovascularization Therapy” L. Gonzalez, R.J. Loza, K.Y. Han, S. Sunoqrot, C. Cunningham, P. Purta, J. Drake, S. Jain, S. Hong, and J.-H. Chang*, Journal of Ocular Pharmacology and Therapeutics 2013, 29(2), 124-134.
35. “The Role of Polymers in Detection and Isolation of Circulating Tumor Cells” J.H. Myung, K.A. Gajjar, Y.E. Han, and S. Hong*, Polymer Chemistry 2012, 3(9), 2336-2341.
34. “Enhanced Oral Bioavailability of a Cancer Preventive Agent (SR13668) by Employing Polymeric Nanoparticles with High Drug Loading” H. Shen, A.A. Banerjee, P. Mlynarska, M. Hautman, S. Hong, I.M. Kapetanovic, A.V. Lyubimov, and Y. Liu*, Journal of Pharmaceutical Sciences 2012, 101(10), 3877-3885.
33. “Dendritic Nanoparticles: The Next Generation of Nanocarriers?” R.M. Pearson, S. Sunoqrot, H.-J. Hsu, J.W. Bae, and S. Hong*, Therapeutic Delivery 2012, 3(8), 941-959.
32. “Effect of Size, Surface Charge and Hydrophobilicty of Poly(amidoamine) Dendrimers on Their Skin Penetration” Y. Yang, S. Sunoqrot, C. Stowell, J. Ji, C.-W. Lee, J.W. Kim, S.A. Khan, and S. Hong*, Biomacromolecules 2012, 13(7), 2154-2162.
31. “Temporal Control over Cellular Targeting through Hybridization of Folate-targeted Dendrimers and PEG-PLA Nanoparticles” S. Sunoqrot, J.W. Bae, R.M. Pearson, K. Shyu, Y. Liu, D.H. Kim, and S. Hong*, Biomacromolecules 2012, 13(4), 1223-1230.
30. “Channel Surface Patterning of Alternating Biomimetic Protein Combinations for Enhanced Microfluidic Tumor Cell Isolation” C.A. Launiere, M. Gaskill, G. Czaplewski, J.H. Myung, S. Hong, and D.T. Eddington*, Analytical Chemistry 2012, 84(9):4022-8.
29. “Dendrimer-mediated Multivalent Binding for Enhanced Capture of Tumor Cells” J.H. Myung, K.A. Gajjar, J. Saric, D.T. Eddington, and S. Hong*, Angewandte Chemie International Edition 2011, 50(49), 11769-11772.
28. “Dendron-mediated Self-assembly of Highly PEGylated Block Copolymers: A Modular Nanocarrier Platform” J.W. Bae, R.M. Pearson, N. Patra, S. Sunoqrot, L. Vukovi, P. Kral, and S. Hong*, Chemical Communications 2011, 47(37), 10302-10304.
27. “Kinetically Controlled Cellular Interactions of Polymer-Polymer and Polymer-Liposome Nanohybrid Systems” S. Sunoqrot, J.W. Bae, S.E. Jin, R.M. Pearson, Y. Liu, and S. Hong*, Bioconjugate Chemistry 2011, 22(3), 466-474.
26. “Self-Assembling Process of Flash Nanoprecipitation in a Multi-inlet Vortex Mixer (MIVM) to Produce Drug-Loaded Polymeric Nanoparticles” H. Shen, S. Hong, R.K. Prud’homme, and Y. Liu*, Journal of Nanoparticle Research 2011, 13(9), 4109-4120.
25. “Rheologically Biomimetic Cell Suspensions for Decreased Cell Settling in Microfluidic Devices” C.A. Launiere, G.J. Czaplewski, J.H. Myung, S. Hong, and D.T. Eddington*, Biomedical Microdevices 2011, 13(3), 549-557.
24. “Direct Measurements on CD24-Mediated Rolling of Human Breast Cancer MCF-7 Cells on E-selectin” J.H. Myung, K.A. Gajjar, R.M. Pearson, C.A. Launiere, D.T. Eddington, and S. Hong*, Analytical Chemistry 2011, 83(3), 1078-1083.
23. “Enhanced Tumor Cell Isolation by a Biomimetic Combination of E-selectin and anti-EpCAM: Implication for Effective Separation of Circulating Tumor Cells (CTCs)” J.H. Myung, C.A. Launiere, D.T. Eddington, and S. Hong*, Langmuir 2010, 26(11), 8589-8596.
22. “Multi-scale Observation of Biological Interactions of Nanocarriers: From Nano to Macro” S.E. Jin, J.W. Bae, and S. Hong*, Microscopy Research and Technique 2010, 73(9), 813-823.
21. “The Role of Gaglioside GM1 in Cellular Internalization Mechanisms of Poly(amidoamine) Dendrimers” S. Hong, R. Rattan, I.J, Majoros, D.G. Mullen, J.L. Peters, X. Shi, A.U. Bielinska, L. Blanco, B.G. Orr, J.R. Baker, and M.M. Banaszak Holl*, Bioconjugate Chemistry 2009, 20(8), 1503-1513.
20. “Cationic Nanoparticles Induce Nanoscale Disruption in Living Cell Plasma Membranes” J. Chen, J.A. Hessler, K. Putchakayala, B.K. Panama, D.P. Khan, S. Hong, D.G. Mullen, S.C. DiMaggio, A. Som, G.N. Tew, A.N. Lopatin, J.R. Baker, M.M. Banaszak Holl*, and B.G. Orr*, Journal of Physical Chemistry B 2009, 113(32), 11179-11185.
19. “Effect of Modified Carbon Nanotube on the Properties of Aromatic Polyester Nanocomposites” J.Y. Kim*, S.I. Han, and S. Hong, Polymer 2008, 49(15), 3335-3345.
18. “Nanomechanical Control of Cell Rolling in Two Dimensions through Surface Patterning of Receptors” R. Karnik, S. Hong, H. Zhang, Y. Mei, D. Anderson, J.M. Karp, and R. Langer*, Nano Letters, 2008, 8(4), 1153-1158.
17. “A Biodegradable and Biocompatible Gecko-Inspired Tissue Adhesive” A. Mahdavi, L. Ferreira, C. Sundback, J.W. Nichol, E.P. Chan, D.J. Carter, C.J. Bettinger, S. Patanavanich, L. Chignozha, E. Ben-Joseph, A. Galakatos, H. Pryor, I. Pomerantseva, P.T. Masiakos, W. Fraquin, A. Zumbuehl, S. Hong, J. Borenstein, J. Vancanti, R. Langer, and J.M. Karp*, Proceedings of the National Academy of Sciences USA, 2008, 105, 2307-2312.
16. “Synthesis, Characterization, and In Vitro Testing of Superparamagnetic Iron Oxide Nanoparticles Targeted Using Folic Acid-Conjugated Dendrimers” K.J. Landmark, S. DiMaggio, J. Ward, S. Vogt, S. Hong, A. Kotlyar, J.E. Penner-Hahn, J.R. Baker, M.M. Banaszak Holl*, and B.G. Orr*, ACS Nano, 2008, 2(4), 773-783.
15. “Nanocarriers as an Emerging Platform for Cancer Therapy” D. Peer#, J.M. Karp#, S. Hong#, O.C. Farokhzad, R. Margalit, and R. Langer*, Nature Nanotechnology 2007, 2, 751-760, #denotes co-first authors.
14. “Covalent Immobilization of P-selectin Enhances Cell Rolling” S. Hong, D. Lee, H. Zhang, J.Q. Zhang, J.N. Resvick, A. Khademhosseini, M.R. King, R. Langer, and J.M. Karp*, Langmuir 2007, 23(24), 12261-12268.
13. “Targeted Nanoparticles for Cancer Therapy” F.X. Gu, R. Karnik, A.Z. Wang, F. Alexis, E. Levy-Nissenbaum, S. Hong, R. Langer, and O.C. Farokhzad*, Nano Today 2007, 2(3), 14-21.
12. “Nanoparticle Interaction with Biological Membranes: Does Nanotechnology Present a Janus Face?” P.R. Leroueil, S. Hong, A. Mecke, J.R. Baker, B.G. Orr, and M.M. Banaszak Holl*, Accounts of Chemical Research 2007, 40(5), 335-342.
11. “The Binding Avidity of A Nanoparticle-Based Multivalent Targeted Drug Delivery Platform” S. Hong, P.R. Leroueil, I.J. Majoros, B.G. Orr, J.R. Baker*, and M.M. Banaszak Holl*, Chemistry & Biology 2007, 14(1), 107-115.
10. “Morphology and Physical Properties of Binary Blend Based on PVDF and Multi-Walled Carbon Nanotube” Y.W. Nam, W.N. Kim, Y.H. Cho, D.W. Chae, G.H. Kim, S. Hong, S.S. Hwang, and S.M. Hong*, Macromolecular Symposia 2007, 249-250, 478-484.
9. “Influence of High Contents of Silver Nanoparticles on the Physical Properties of Poly(vinyliden fluoride)” D.W. Chae, S.S. Hwang, S.M. Hong, S. Hong, B.G. Cho, and B.C. Kim*, Molecular Crystals & Liquid Crystals 2007, 464, 233-241.
8. “The Interaction of Polycationic Polymers with Supported Lipid Bilayers and Cells: Nanoscale Hole Formation and Enhanced Membrane Permeability” S. Hong, P.R. Leroueil, E.K. Janus, J.L. Peters, M.-M. Kober, M.T. Islam, B.G. Orr, J.R. Baker, and M.M. Banaszak Holl*, Bioconjugate Chemistry 2006, 17(3), 728-734. (An ACS Most-Cited Article 2006)
7. “HPLC Analysis of Functionalized Poly(amidoamine) Dendrimer Derivatives and Their Bindings with a Specific Protein” X. Shi, X. Bi, T.R. Ganser, S. Hong, L.A. Myc, A. Desai, M.M. Banaszak Holl, and J.R. Baker*, Analyst 2006, 131(7), 842-848.
6. “Physical Interactions of Nanoparticles with Biological Membranes: The Observation of Nanoscale Hole Formation” S. Hong, J.A. Hessler, M.M. Banaszak Holl*, P.R. Leroueil, A. Mecke, and B.G. Orr, Journal of Chemical Health & Safety 2006, 13(3), 16-20.
5. “The Interaction of Polyamidoamine (PAMAM) Dendrimers with Supported Lipid Bilayers and Cells: Hole Formation and the Relation to Transport” S. Hong, A.U. Bielinska, A. Mecke, B. Keszler, J.L. Beals, X. Shi, L. Balogh, B.G. Orr, J.R. Baker, and M.M. Banaszak Holl*, Bioconjugate Chemistry 2004, 15(4), 774-782.
4. “Effect of Poly(esterimide)s as Compatibilizers on the Physical Properties of Poly(etherimide)/ Thermotropic Liquid Crystalline Polymer in-situ Composites” S. Hong, Y.S. Gil, S.S. Hwang, and S.M. Hong*, Polymer Journal 2004, 36(4), 271-283.
3. “Characterization and Physical Properties of Polymethylphenylsilsesquioxane (PMPSQ) and Hydroxyl-Functionalized Polystyrene (PS-OH) Hybrids” S. Hong, S.M. Hong*, S.S. Hwang, and B.C. Kim, Journal of Applied Polymer Science 2003, 90, 2801-2812.
2. “Optimization of Foaming Process using Triblock Polyimides with Thermally Labile Blocks” D.W. Kim, S.S. Hwang*, S.M. Hong, Y.H. Yoo, and S. Hong, Polymer 2001, 42, 83-92.
1. “High Functional Polyorganosilsesquioxanes” E.C. Lee, S. Hong, S.S. Hwang, and S.M. Hong*, Polymer Science & Technology (Korean) 2000, 11(5), 634-642.