Marker Lab

Publications

  1. Unterberger, C. J., McIlwain, S. J., Tsourkas, P. K., Maklakova, V. I., Prince, J. L., Onesti, A., Hu, R., Kopchick, J. J., Swanson, S. M., & Marker, P. C. (2023). Conditional gene regulation models demonstrate a pro-proliferative role for growth hormone receptor in prostate cancer.. The Prostate, 83(5), 416-429. https://doi.org/10.1002/pros.24474
  2. Marker, P. C., Unterberger, C. J., & Swanson, S. M. (2023). GH-dependent growth of experimentally induced carcinomas in vivo.. Endocrine-related cancer, 30(5). https://doi.org/10.1530/ERC-22-0403
  3. Unterberger, C. J., McIlwain, S. J., Tsourkas, P. K., Maklakova, V. I., Prince, J. L., Onesti, A., Hu, R., Kopchick, J. J., Swanson, S. M., & Marker, P. C. (2022). Conditional gene regulation models demonstrate a pro-proliferative role for growth hormone receptor in prostate cancer.. The Prostate. https://doi.org/10.1002/pros.24474
  4. Unterberger, C. J., McGregor, S. M., Kopchick, J. J., Swanson, S. M., & Marker, P. C. (2022). Mammary Tumor Growth and Proliferation Are Dependent on Growth Hormone in Female SV40 C3(1) T-Antigen Mice.. Endocrinology, 164(2). https://doi.org/10.1210/endocr/bqac174
  5. Unterberger, C. J., Maklakova, V. I., Lazar, M., Arneson, P. D., Mcilwain, S. J., Tsourkas, P. K., Hu, R., Kopchick, J. J., Swanson, S. M., & Marker, P. C. (2022). GH Action in Prostate Cancer Cells Promotes Proliferation, Limits Apoptosis, and Regulates Cancer-related Gene Expression.. Endocrinology, 163(5). https://doi.org/10.1210/endocr/bqac031
  6. , Unterberger, C. J., Ye, Z., Feltenberger, J. B., Swanson, S. M., Marker, P. C., & Kwon, G. S. (2021). Oligo(lactic acid)8-docetaxel prodrug-loaded peg-b-pla micelles for prostate cancer. Nanomaterials(11), 2745. https://doi.org/https://doi.org/ 10.3390/nano11102745
  7. Lantvit, D. D., Unterberger, C. J., Lazar, M., Arneson, P. D., Longhurst, C. A., Swanson, S. M., & Marker, P. C. (2021). Mammary Tumors Growing in the Absence of Growth Hormone Are More Sensitive to Doxorubicin Than Wild-Type Tumors.. Endocrinology, 162(4). https://doi.org/10.1210/endocr/bqab013
  8. Wegner, K. A., Ruetten, H., Girardi, N. M., O’Driscoll, C. A., Sandhu, J. K., Turco, A. E., Abler, L. L., Wang, P., Wang, Z., Bjorling, D. E., Malinowski, R., Peterson, R. E., Strand, D. W., Marker, P. C., & Vezina, C. M. (2021). Genetic background but not prostatic epithelial beta-catenin influences susceptibility of male mice to testosterone and estradiol-induced urinary dysfunction.. American journal of clinical and experimental urology, 9(1), 121-131.
  9. Wei, P., Hao, L., Thomas, S., Buchberger, A. R., Steinke, L., Marker, P. C., Ricke, W. A., & Li, L. (2020). Urinary Amine Metabolomics Characterization with Custom 12-Plex Isobaric DiLeu Labeling. Journal of the American Society for Mass Spectrometry, 31(9), 1854-1860.
  10. Thomas, S., Hao, L., DeLaney, K., McLean, D., Steinke, L., Marker, P. C., Vezina, C. M., Li , L., & Ricke, W. A. (2020). Spatiotemporal Proteomics Reveals the Molecular Consequences of Hormone Treatment in a Mouse Model of Lower Urinary Tract Dysfunction.. Journal of proteome research, 19(4), 1375-1382. https://doi.org/10.1021/acs.jproteome.9b00451
  11. Ruetten, H., Wegner, K. A., Kennedy, C. L., Turco, A., Zhang, H. L., Wang, P., Sandhu, J., Sandhu, S., Morkrid, J., Wang, Z., Macoska, J., Peterson, R. E., Bjorling, D. E., Ricke, W. A., Marker, P. C., & Vezina, C. M. (2020). Impact of sex, androgens, and prostate size on C57BL/6J mouse urinary physiology: urethral histology.. American journal of physiology. Renal physiology, 318(3), F617-F627. https://doi.org/10.1152/ajprenal.00540.2019
  12. Thomas, S., Hao, L., DeLaney, K., McLean, D., Steinke, L., Marker, P. C., Vezina, C. M., Li, L., & Ricke, W. A. (2020). Spatiotemporal proteomics reveals the molecular consequences of hormone treatment in a mouse model of lower urinary tract dysfunction. Journal of proteome research, 19(4), 1375-1382.
  13. Wegner, K. A., Mueller, B. R., Unterberger, C. J., Avila, E. J., Ruetten, H., Turco, A. E., Oakes, S. R., Girardi, N. M., Halberg, R. B., Swanson, S. M., Marker, P. C., & Vezina, C. M. (2020). Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation.. The Journal of pathology, 250(2), 231-242. https://doi.org/10.1002/path.5363
  14. Ruetten, H., Wegner, K. A., Zhang, H. L., Wang, P., Sandhu, J., Sandhu, S., Morkrid, J., Mueller, B., Wang, Z., Macoska, J., Peterson, R. E., Bjorling, D. E., Ricke, W. A., Marker, P. C., & Vezina, C. M. (2019). Insight and Resources From a Study of the “Impact of Sex, Androgens, and Prostate Size on C57BL/6J Mouse Urinary Physiology.. Toxicologic pathology, 47(8), 1038-1042. https://doi.org/10.1177/0192623319877867
  15. Ruetten, H., Wegner, K. A., Zhang, H. L., Wang, P., Sandhu, J., Sandhu, S., Mueller, B., Wang, Z., Macoska, J., Peterson, R. E., Bjorling, D. E., Ricke, W. A., Marker, P. C., & Vezina, C. M. (2019). Impact of sex, androgens, and prostate size on C57BL/6J mouse urinary physiology: functional assessment.. American journal of physiology. Renal physiology, 317(4), F996-F1009. https://doi.org/10.1152/ajprenal.00270.2019
  16. Liu, T. T., Rodgers, A. C., Nicholson, T. M., Macoska, J. A., Marker, P. C., Vezina, C. M., Bjorling, D. E., Roldan-Alzate, A., Hernando, D., Lloyd, G. L., Hacker, T. A., & Ricke, W. A. (2019). Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing.. Journal of visualized experiments : JoVE(150). https://doi.org/10.3791/59802
  17. Wegner, K. A., Mehta, V., Johansson, J. A., Mueller, B. R., Keil, K. P., Abler, L. L., Marker, P. C., Taketo, M. M., Headon, D. J., & Vezina, C. M. (2019). Edar is a downstream target of beta-catenin and drives collagen accumulation in the mouse prostate.. Biology open. https://doi.org/10.1242/bio.037945
  18. Wegner, K. A., Abler, L. L., Oakes, S. R., Mehta, G. S., Ritter, K. E., Hill, W. G., Zwaans, B. M., Lamb, L. E., Wang, Z., Bjorling, D. E., Ricke, W. A., Macoska, J., Marker, P. C., Southard-Smith, E. M., Eliceiri, K. W., & Vezina, C. M. (2018). Void spot assay procedural optimization and software for rapid and objective quantification of rodent voiding function, including overlapping urine spots.. American journal of physiology. Renal physiology, 315(4), F1067-F1080. https://doi.org/10.1152/ajprenal.00245.2018
  19. Ruetten, H., Wegner, K. A., Romero, M. F., Wood, M. W., Marker, P. C., Strand, D., Colopy, S. A., & Vezina, C. M. (2018). Prostatic collagen architecture in neutered and intact canines.. The Prostate, 78(11), 839-848. https://doi.org/10.1002/pros.23641
  20. Le, B., Powers, G. L., Tam, Y. T., Schumacher, N., Malinowski, R. L., Steinke, L., Kwon, G., & Marker, P. C. (2017). Multi-drug loaded micelles delivering chemotherapy and targeted therapies directed against HSP90 and the PI3K/AKT/mTOR pathway in prostate cancer. PLOS One, 12, e0174658. https://doi.org/https://doi.org/10.1371/journal.pone.0174658
  21. Hao, L., Greer, T., Page, D., Shi, Y., Vezina, C. M., Macoska, J. A., Marker, P. C., Bjorling, D. E., Bushman, W., Ricke, W. A., & others (2016). In-depth characterization and validation of human urine metabolomes reveal novel metabolic signatures of lower urinary tract symptoms. Scientific reports, 6, 30869.
  22. Keil, K. P., Abler, L. L., Altmann, H. M., Bushman, W., Marker, P. C., Li, L., Ricke, W. A., Bjorling, D. E., & Vezina, C. M. (2016). Influence of animal husbandry practices on void spot assay outcomes in C57BL/6J male mice. Neurourology and urodynamics, 35(2), 192–198.
  23. Hao, L., Greer, T., Page, D., Shi, Y., Vezina, C. M., Macoska, J. A., Marker, P. C., Bjorling, D. E., Bushman, W., Ricke, W. A., & Li, L. (2016). In-Depth Characterization and Validation of Human Urine Metabolomes Reveal Novel Metabolic Signatures of Lower Urinary Tract Symptoms. Scientific Reports, 6, 30869.
  24. Keil, K. P., Abler, L. L., Altmann, H. M., Bushman, W., Marker, P. C., Li , L., Ricke, W. A., Bjorling, D. E., & Vezina, C. M. (2016). Influence of animal husbandry practices on void spot assay outcomes in C57BL/6J male mice.. Neurourology and urodynamics, 35(2), 192-8. https://doi.org/10.1002/nau.22692
  25. Greer, T., Hao, L., Nechyporenko, A., Lee, S., Vezina, C. M., Ricke, W. A., Marker, P. C., Bjorling, D. E., Bushman, W., & Li, L. (2015). Custom 4-plex DiLeu isobaric labels enable relative quantification of urinary proteins in men with lower urinary tract symptoms (LUTS). PloS one, 10(8), e0135415.
  26. Powers, G. L., Hammer, K. D., Domenech, M., Frantskevich, K., Malinowski, R. L., Bushman, W., Beebe, D. J., & Marker, P. C. (2015). Phosphodiesterase 4D inhibitors limit prostate cancer growth potential.. Molecular cancer research : MCR, 13(1), 149-60. https://doi.org/10.1158/1541-7786.MCR-14-0110