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Negative side effects of opioids could be coming from users’ own immune systems (video)

Posted on August 11, 2020
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DARK Classics in Chemical Neuroscience: Synthetic Cannabinoids (Spice/K2)

Posted on December 4, 2019

Abstract This Review covers the background, pharmacology, adverse effects, synthesis, pharmacokinetics, metabolism, and history of synthetic cannabinoid compounds. Synthetic cannabinoids are a class of novel psychoactive substances that act as agonists at cannabinoid receptors. This …

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Can a Trip-Free Psychedelic Still Help People With Depression?

Posted on November 7, 2019
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Protesters voice concerns about lack of pain medication

Posted on October 16, 2019
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Ghrelin Receptor Influence on Cocaine Reward is Not Directly Dependent on Peripheral Acyl-Ghrelin

Posted on February 12, 2019

Abstract The peptide hormone acyl-ghrelin and its receptor, GHSR1a, represent intriguing therapeutic targets due to their actions in metabolic homeostasis and reward activity. However, this pleotropic activity makes it difficult to intervene in this system …

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The search for vaccines against street drugs

Posted on August 19, 2017
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Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction

Posted on January 15, 2015

Abstract Clinical studies have revealed that genetic variations in metabotropic glutamate receptor 3 (mGlu3) affect performance on cognitive tasks dependent upon the prefrontal cortex (PFC) and may be linked to psychiatric conditions such as schizophrenia, …

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