{"id":37,"date":"2024-07-26T15:46:31","date_gmt":"2024-07-26T15:46:31","guid":{"rendered":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/rose-laboratory\/?page_id=37"},"modified":"2024-07-26T15:56:19","modified_gmt":"2024-07-26T15:56:19","slug":"mechanism-and-pharmacodynamics-of-glyco-lipopeptide-synergy-with-older-antimicrobials","status":"publish","type":"page","link":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/research\/mechanism-and-pharmacodynamics-of-glyco-lipopeptide-synergy-with-older-antimicrobials\/","title":{"rendered":"Mechanism and pharmacodynamics of glyco\/lipopeptide synergy with older antimicrobials"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"Antibiotic resistance or tolerance to primary anti-Gram-positive therapies, such as \u03b2-lactams, vancomycin, and daptomycin often leads to poor clinical outcomes and dramatic increases in health-care expenditures. Approximately 30% of patients with\u00a0Staphylococcus aureus\u00a0bacteremia and exhibit primary therapeutic failures, with in-hospital mortality rates approaching 20% despite receiving seemingly appropriate antimicrobial therapy. In addition, persistent bacteremias, despite in…","protected":false},"author":7,"featured_media":0,"parent":8,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-37","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/wp-json\/wp\/v2\/pages\/37","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/wp-json\/wp\/v2\/comments?post=37"}],"version-history":[{"count":2,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/wp-json\/wp\/v2\/pages\/37\/revisions"}],"predecessor-version":[{"id":3580,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/wp-json\/wp\/v2\/pages\/37\/revisions\/3580"}],"up":[{"embeddable":true,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/wp-json\/wp\/v2\/pages\/8"}],"wp:attachment":[{"href":"https:\/\/pharmacy.wisc.edu\/faculty\/rose-laboratory\/wp-json\/wp\/v2\/media?parent=37"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}