{"id":281,"date":"2011-10-19T18:59:52","date_gmt":"2011-10-19T18:59:52","guid":{"rendered":"https:\/\/wwwtest.pharmacy.wisc.edu\/faculty\/hong-research-group\/?p=281"},"modified":"2025-06-20T19:02:27","modified_gmt":"2025-06-20T19:02:27","slug":"dendrimer-mediated-multivalent-binding-for-enhanced-capture-of-tumor-cells","status":"publish","type":"post","link":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/2011\/10\/19\/dendrimer-mediated-multivalent-binding-for-enhanced-capture-of-tumor-cells\/","title":{"rendered":"Dendrimer-mediated Multivalent Binding for Enhanced Capture of Tumor Cells"},"content":{"rendered":"

Abstract<\/h2>\r\n
\r\n\r\nA naturally occurring\u00a0multivalent binding effect is manipulated by engineering cell capture surfaces using dendrimers. The enhanced binding through the multivalent effect significantly improves detection of tumor cells. This improvement can be potentially translated into clinically significant detection of circulating tumor cells from the blood of cancer patients.\r\n\r\n\"visualization\r\n\r\n
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Cited by<\/h2>\r\nThis article is cited by 55 publications\r\n
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    Liu, J., Gray, W. D., Davis, M. E., & Luo, Y. (2012). Peptide- and saccharide-conjugated dendrimers for targeted drug delivery: a concise review.\u00a0Interface focus<\/i>,\u00a02<\/i>(3), 307\u2013324.\u00a0https:\/\/doi.org\/10.1098\/rsfs.2012.0009<\/a><\/div><\/li>\r\n \t
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    Sunoqrot, S., Bae, J. W., Pearson, R. M., Shyu, K., Liu, Y., Kim, D. H., & Hong, S. (2012). Temporal control over cellular targeting through hybridization of folate-targeted dendrimers and PEG-PLA nanoparticles.\u00a0Biomacromolecules<\/i>,\u00a013<\/i>(4), 1223\u20131230.\u00a0https:\/\/doi.org\/10.1021\/bm300316n<\/a><\/div><\/li>\r\n<\/ol>\r\n<\/div>","protected":false},"excerpt":{"rendered":"Abstract A naturally occurring\u00a0multivalent binding effect is manipulated by engineering cell capture surfaces using dendrimers. The enhanced binding through the multivalent effect significantly improves detection of tumor cells. This improvement can be potentially translated into …","protected":false},"author":7,"featured_media":283,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-281","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications"],"acf":[],"_links":{"self":[{"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/posts\/281","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/comments?post=281"}],"version-history":[{"count":1,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/posts\/281\/revisions"}],"predecessor-version":[{"id":284,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/posts\/281\/revisions\/284"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/media\/283"}],"wp:attachment":[{"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/media?parent=281"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/categories?post=281"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmacy.wisc.edu\/faculty\/hong-research-group\/wp-json\/wp\/v2\/tags?post=281"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}