Transdisciplinary Center for Research in Psychoactive Substances
Glowing mushrooms release psilocybin to a brain

Research

Advancing research in the emerging field of psychedelic compounds

Members of the University of Wisconsin–Madison Transdisciplinary Center for Research in Psychoactive Substances are engaged in research that cuts across multiple disciplines and engages with science and society. Center members work together and individually to better understand the psychoactive substances in the lab, clinical settings, and in within the humanities.

Members of the Center are engaged in Phase 1-3 clinical trials of psychedelic and psychoactive compounds.  Some of these trials are part of multi-site Phase 2 and 3 trials making their way toward New Drug Applications with the FDA.  Other early stage studies are exploratory, often mechanistic studies of these agents in humans as well as animal models.

Members also currently engage in cultural, legal, economic, and historical research and this body of scholarship comes from departments and divisions across the UW campus.

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Interested in Participating in a Clinical Study?

At this time, we do not have active studies directed toward the treatment of adult depression or adult post-traumatic stress disorder (PTSD). Please note our Active Clinical Studies are listed in the tabs to the left.

Other sites that may be testing psychoactive-assisted therapy for depression, anxiety, or PTSD may be found at clinicaltrials.gov.

If you are interested in participating in a clinical trial of psilocybin for the treatment of opioid use disorder or methamphetamine use disorder, please send an email indicating your interest to: protea.research@mailplus.wisc.edu.

A new clinical study of administering IV psilocybin to healthy young adults while asleep (the CoPE trial) has recently been opened.  Please note the contact information under the Active Clinical Studies tab.